Cherney RJ - Search Results

1

Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2).

Yang MG, Xiao Z, Shi Q, Cherney RJ, Tebben AJ, De Lucca GV, Santella JB 3rd, Mo R, Cvijic ME, Zhao Q, Barrish JC, Carter PH. Yang MG, et al. Among authors: cherney rj. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1384-7. doi: 10.1016/j.bmcl.2011.12.057. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22225639

2

Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2).

Carter PH, Brown GD, Friedrich SR, Cherney RJ, Tebben AJ, Lo YC, Yang G, Jezak H, Solomon KA, Scherle PA, Decicco CP. Carter PH, et al. Among authors: cherney rj. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5455-61. doi: 10.1016/j.bmcl.2007.07.028. Epub 2007 Jul 21. Bioorg Med Chem Lett. 2007. PMID: 17720492

3

Discovery of disubstituted cyclohexanes as a new class of CC chemokine receptor 2 antagonists.

Cherney RJ, Mo R, Meyer DT, Nelson DJ, Lo YC, Yang G, Scherle PA, Mandlekar S, Wasserman ZR, Jezak H, Solomon KA, Tebben AJ, Carter PH, Decicco CP. Cherney RJ, et al. J Med Chem. 2008 Feb 28;51(4):721-4. doi: 10.1021/jm701488f. Epub 2008 Jan 31. J Med Chem. 2008. PMID: 18232650

4

Synthesis and evaluation of cis-3,4-disubstituted piperidines as potent CC chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Nelson DJ, Lo YC, Yang G, Scherle PA, Jezak H, Solomon KA, Carter PH, Decicco CP. Cherney RJ, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5063-5. doi: 10.1016/j.bmcl.2008.07.123. Epub 2008 Aug 5. Bioorg Med Chem Lett. 2008. PMID: 18722120

5

Discovery of trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Brogan JB, Mo R, Lo YC, Yang G, Miller PB, Scherle PA, Molino BF, Carter PH, Decicco CP. Cherney RJ, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):597-601. doi: 10.1016/j.bmcl.2008.12.062. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19131247

6

Novel sulfone-containing di- and trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Mo R, Meyer DT, Voss ME, Lo YC, Yang G, Miller PB, Scherle PA, Tebben AJ, Carter PH, Decicco CP. Cherney RJ, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3418-22. doi: 10.1016/j.bmcl.2009.05.041. Epub 2009 May 18. Bioorg Med Chem Lett. 2009. PMID: 19481449

7

gamma-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Mo R, Meyer DT, Voss ME, Yang MG, Santella JB 3rd, Duncia JV, Lo YC, Yang G, Miller PB, Scherle PA, Zhao Q, Mandlekar S, Cvijic ME, Barrish JC, Decicco CP, Carter PH. Cherney RJ, et al. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2425-30. doi: 10.1016/j.bmcl.2010.03.035. Epub 2010 Mar 10. Bioorg Med Chem Lett. 2010. PMID: 20346664

8

Discovery of an orally-bioavailable CC Chemokine Receptor 2 antagonist derived from an acyclic diaminoalcohol backbone.

Carter PH, Brown GD, King SR, Voss ME, Tebben AJ, Cherney RJ, Mandlekar S, Lo YC, Yang G, Miller PB, Scherle PA, Zhao Q, Decicco CP. Carter PH, et al. Among authors: cherney rj. Bioorg Med Chem Lett. 2012 May 1;22(9):3311-6. doi: 10.1016/j.bmcl.2012.03.007. Epub 2012 Mar 10. Bioorg Med Chem Lett. 2012. PMID: 22475558

9

Benzimidazoles as benzamide replacements within cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Mo R, Meyer DT, Pechulis AD, Guaciaro MA, Lo YC, Yang G, Miller PB, Scherle PA, Zhao Q, Cvijic ME, Barrish JC, Decicco CP, Carter PH. Cherney RJ, et al. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6181-4. doi: 10.1016/j.bmcl.2012.08.002. Epub 2012 Aug 10. Bioorg Med Chem Lett. 2012. PMID: 22939233

10

Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists.

Cherney RJ, Mo R, Yang MG, Xiao Z, Zhao Q, Mandlekar S, Cvijic ME, Charo IF, Barrish JC, Decicco CP, Carter PH. Cherney RJ, et al. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1843-5. doi: 10.1016/j.bmcl.2014.02.013. Epub 2014 Feb 21. Bioorg Med Chem Lett. 2014. PMID: 24613378 Free PMC article.

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