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RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.
Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, DeMartino J, Fine JS. Xu D, et al. Among authors: kim y. J Pharmacol Exp Ther. 2012 Apr;341(1):90-103. doi: 10.1124/jpet.111.187740. Epub 2012 Jan 6. J Pharmacol Exp Ther. 2012. PMID: 22228807
Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
Mina-Osorio P, LaStant J, Keirstead N, Whittard T, Ayala J, Stefanova S, Garrido R, Dimaano N, Hilton H, Giron M, Lau KY, Hang J, Postelnek J, Kim Y, Min S, Patel A, Woods J, Ramanujam M, DeMartino J, Narula S, Xu D. Mina-Osorio P, et al. Among authors: kim y. Arthritis Rheum. 2013 Sep;65(9):2380-91. doi: 10.1002/art.38047. Arthritis Rheum. 2013. PMID: 23754328 Free article.
Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.
Liao C, Hsu J, Kim Y, Hu DQ, Xu D, Zhang J, Pashine A, Menke J, Whittard T, Romero N, Truitt T, Slade M, Lukacs C, Hermann J, Zhou M, Lucas M, Narula S, DeMartino J, Tan SL. Liao C, et al. Among authors: kim y. Arthritis Res Ther. 2013 Oct 4;15(5):R146. doi: 10.1186/ar4329. Arthritis Res Ther. 2013. PMID: 24286216 Free PMC article.
Effectiveness and Safety of Polydioxanone Thread Embedding Acupuncture Compared with Acupuncture Treatment for Knee Osteoarthritis: a Protocol for a Pilot, Assessor-Blinded, Randomized Controlled Trial.
Jang HJ, Han CH, Jeon JH, Jeong JK, Zhao H, Yang C, Seo BN, Kwon O, Sun W, Ran J, Xu H, Kim YI. Jang HJ, et al. Among authors: kim yi. J Acupunct Meridian Stud. 2024 Dec 31;17(6):210-220. doi: 10.51507/j.jams.2024.17.6.210. J Acupunct Meridian Stud. 2024. PMID: 39722644 Clinical Trial.
Unbiased Drug Target Prediction Reveals Sensitivity to Ferroptosis Inducers, HDAC and RTK Inhibitors in Melanoma Subtypes.
Pla I, Szabolcs BL, Péter PN, Ujfaludi Z, Kim Y, Horvatovich P, Sanchez A, Pawlowski K, Wieslander E, Kuras M, Murillo JR, Guedes J, Pál DMP, Ascsillán AA, Betancourt LH, Németh IB, Gil J, de Almeida NP, Szeitz B, Szadai L, Doma V, Woldmar N, Bartha Á, Pahi Z, Pankotai T, Győrffy B, Szasz AM, Domont G, Nogueira F, Kwon HJ, Appelqvist R, Kárpáti S, Fenyö D, Malm J, Marko-Varga G, Kemény LV. Pla I, et al. Among authors: kim y. Int J Dermatol. 2024 Dec 25. doi: 10.1111/ijd.17586. Online ahead of print. Int J Dermatol. 2024. PMID: 39722169
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