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mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation.
Sinclair C, Bommakanti G, Gardinassi L, Loebbermann J, Johnson MJ, Hakimpour P, Hagan T, Benitez L, Todor A, Machiah D, Oriss T, Ray A, Bosinger S, Ravindran R, Li S, Pulendran B. Sinclair C, et al. Among authors: loebbermann j. Science. 2017 Sep 8;357(6355):1014-1021. doi: 10.1126/science.aaj2155. Epub 2017 Aug 10. Science. 2017. PMID: 28798047 Free PMC article.
The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation.
Ravindran R, Loebbermann J, Nakaya HI, Khan N, Ma H, Gama L, Machiah DK, Lawson B, Hakimpour P, Wang YC, Li S, Sharma P, Kaufman RJ, Martinez J, Pulendran B. Ravindran R, et al. Among authors: loebbermann j. Nature. 2016 Mar 24;531(7595):523-527. doi: 10.1038/nature17186. Epub 2016 Mar 16. Nature. 2016. PMID: 26982722 Free PMC article.