Schmalhofer WA - Search Results

1

Selective, direct activation of high-conductance, calcium-activated potassium channels causes smooth muscle relaxation.

Ponte CG, McManus OB, Schmalhofer WA, Shen DM, Dai G, Stevenson A, Sur S, Shah T, Kiss L, Shu M, Doherty JB, Nargund R, Kaczorowski GJ, Suarez-Kurtz G, Garcia ML. Ponte CG, et al. Among authors: schmalhofer wa. Mol Pharmacol. 2012 Apr;81(4):567-77. doi: 10.1124/mol.111.075853. Epub 2012 Jan 12. Mol Pharmacol. 2012. PMID: 22241372

2

Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function.

Schmalhofer WA, Sanchez M, Dai G, Dewan A, Secades L, Hanner M, Knaus HG, McManus OB, Kohler M, Kaczorowski GJ, Garcia ML. Schmalhofer WA, et al. Biochemistry. 2005 Aug 2;44(30):10135-44. doi: 10.1021/bi050527u. Biochemistry. 2005. PMID: 16042390

3

Purification and functional reconstitution of high-conductance calcium-activated potassium channel from smooth muscle.

Garcia ML, Giangiacomo KM, Hanner M, Knaus HG, McManus OB, Schmalhofer WA, Kaczorowski GJ. Garcia ML, et al. Among authors: schmalhofer wa. Methods Enzymol. 1999;294:274-87. doi: 10.1016/s0076-6879(99)94017-x. Methods Enzymol. 1999. PMID: 9916233 No abstract available.

4

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

Schmalhofer WA, Calhoun J, Burrows R, Bailey T, Kohler MG, Weinglass AB, Kaczorowski GJ, Garcia ML, Koltzenburg M, Priest BT. Schmalhofer WA, et al. Mol Pharmacol. 2008 Nov;74(5):1476-84. doi: 10.1124/mol.108.047670. Epub 2008 Aug 26. Mol Pharmacol. 2008. PMID: 18728100

5

A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.

Schmalhofer WA, Swensen AM, Thomas BS, Felix JP, Haedo RJ, Solly K, Kiss L, Kaczorowski GJ, Garcia ML. Schmalhofer WA, et al. Assay Drug Dev Technol. 2010 Dec;8(6):714-26. doi: 10.1089/adt.2010.0351. Assay Drug Dev Technol. 2010. PMID: 21158686

6

The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding.

Hanner M, Vianna-Jorge R, Kamassah A, Schmalhofer WA, Knaus HG, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. J Biol Chem. 1998 Jun 26;273(26):16289-96. doi: 10.1074/jbc.273.26.16289. J Biol Chem. 1998. PMID: 9632689 Free article.

7

Pharmacology of potassium channels.

Garcia ML, Hanner M, Knaus HG, Koch R, Schmalhofer W, Slaughter RS, Kaczorowski GJ. Garcia ML, et al. Adv Pharmacol. 1997;39:425-71. doi: 10.1016/s1054-3589(08)60078-2. Adv Pharmacol. 1997. PMID: 9160122 Review. No abstract available.

8

The beta subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin.

Hanner M, Schmalhofer WA, Munujos P, Knaus HG, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2853-8. doi: 10.1073/pnas.94.7.2853. Proc Natl Acad Sci U S A. 1997. PMID: 9096310 Free PMC article.

9

Revealing the molecular determinants of neurotoxin specificity for calcium-activated versus voltage-dependent potassium channels.

Giangiacomo KM, Becker J, Garsky C, Felix JP, Priest BT, Schmalhofer W, Garcia ML, Mullmann TJ. Giangiacomo KM, et al. Biochemistry. 2007 May 8;46(18):5358-64. doi: 10.1021/bi700150t. Epub 2007 Apr 18. Biochemistry. 2007. PMID: 17439246

10

A KV2.1 gating modifier binding assay suitable for high throughput screening.

Schmalhofer WA, Ratliff KS, Weinglass A, Kaczorowski GJ, Garcia ML, Herrington J. Schmalhofer WA, et al. Channels (Austin). 2009 Nov;3(6):437-47. doi: 10.4161/chan.3.6.10201. Channels (Austin). 2009. PMID: 21150283 Free article.

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