Khokha R - Search Results

1

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.

McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW. McIlwain DR, et al. Among authors: khokha r. Science. 2012 Jan 13;335(6065):229-32. doi: 10.1126/science.1214448. Science. 2012. PMID: 22246778 Free PMC article.

2

Tissue inhibitor of metalloproteinase 3 regulates TNF-dependent systemic inflammation.

Smookler DS, Mohammed FF, Kassiri Z, Duncan GS, Mak TW, Khokha R. Smookler DS, et al. Among authors: khokha r. J Immunol. 2006 Jan 15;176(2):721-5. doi: 10.4049/jimmunol.176.2.721. J Immunol. 2006. PMID: 16393953

3

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.

Murthy A, Defamie V, Smookler DS, Di Grappa MA, Horiuchi K, Federici M, Sibilia M, Blobel CP, Khokha R. Murthy A, et al. Among authors: khokha r. J Clin Invest. 2010 Aug;120(8):2731-44. doi: 10.1172/JCI42686. Epub 2010 Jul 12. J Clin Invest. 2010. PMID: 20628198 Free PMC article.

4

Metalloproteinases and their natural inhibitors in inflammation and immunity.

Khokha R, Murthy A, Weiss A. Khokha R, et al. Nat Rev Immunol. 2013 Sep;13(9):649-65. doi: 10.1038/nri3499. Nat Rev Immunol. 2013. PMID: 23969736 Review.

5

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

Hakem A, Sanchez-Sweatman O, You-Ten A, Duncan G, Wakeham A, Khokha R, Mak TW. Hakem A, et al. Among authors: khokha r. Genes Dev. 2005 Sep 1;19(17):1974-9. doi: 10.1101/gad.1310805. Epub 2005 Aug 17. Genes Dev. 2005. PMID: 16107613 Free PMC article.

6

Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis.

Murthy A, Shao YW, Narala SR, Molyneux SD, Zúñiga-Pflücker JC, Khokha R. Murthy A, et al. Among authors: khokha r. Immunity. 2012 Jan 27;36(1):105-19. doi: 10.1016/j.immuni.2012.01.005. Immunity. 2012. PMID: 22284418 Free article.

7

Stromal TIMP3 regulates liver lymphocyte populations and provides protection against Th1 T cell-driven autoimmune hepatitis.

Murthy A, Shao YW, Defamie V, Wedeles C, Smookler D, Khokha R. Murthy A, et al. Among authors: khokha r. J Immunol. 2012 Mar 15;188(6):2876-83. doi: 10.4049/jimmunol.1102199. Epub 2012 Feb 8. J Immunol. 2012. PMID: 22323541

8

Clipping, shedding and RIPping keep immunity on cue.

Murphy G, Murthy A, Khokha R. Murphy G, et al. Among authors: khokha r. Trends Immunol. 2008 Feb;29(2):75-82. doi: 10.1016/j.it.2007.10.009. Epub 2008 Jan 7. Trends Immunol. 2008. PMID: 18182322 Review.

9

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.

Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP. Le Gall SM, et al. Among authors: khokha r. J Cell Sci. 2010 Nov 15;123(Pt 22):3913-22. doi: 10.1242/jcs.069997. Epub 2010 Oct 27. J Cell Sci. 2010. PMID: 20980382 Free PMC article.

10

TIMP3 controls cell fate to confer hepatocellular carcinoma resistance.

Defamie V, Sanchez O, Murthy A, Khokha R. Defamie V, et al. Among authors: khokha r. Oncogene. 2015 Jul 30;34(31):4098-108. doi: 10.1038/onc.2014.339. Epub 2014 Oct 27. Oncogene. 2015. PMID: 25347747

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