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Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.
Fougerat A, Gayral S, Gourdy P, Schambourg A, Rückle T, Schwarz MK, Rommel C, Hirsch E, Arnal JF, Salles JP, Perret B, Breton-Douillon M, Wymann MP, Laffargue M. Fougerat A, et al. Circulation. 2008 Mar 11;117(10):1310-7. doi: 10.1161/CIRCULATIONAHA.107.720466. Epub 2008 Feb 11. Circulation. 2008. PMID: 18268153
Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway.
Gayral S, Garnotel R, Castaing-Berthou A, Blaise S, Fougerat A, Berge E, Montheil A, Malet N, Wymann MP, Maurice P, Debelle L, Martiny L, Martinez LO, Pshezhetsky AV, Duca L, Laffargue M. Gayral S, et al. Among authors: fougerat a. Cardiovasc Res. 2014 Apr 1;102(1):118-27. doi: 10.1093/cvr/cvt336. Epub 2013 Dec 19. Cardiovasc Res. 2014. PMID: 24357053
Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low-Density Lipoproteins and Increasing Their Uptake by Macrophages.
Demina EP, Smutova V, Pan X, Fougerat A, Guo T, Zou C, Chakraberty R, Snarr BD, Shiao TC, Roy R, Orekhov AN, Miyagi T, Laffargue M, Sheppard DC, Cairo CW, Pshezhetsky AV. Demina EP, et al. Among authors: fougerat a. J Am Heart Assoc. 2021 Feb 16;10(4):e018756. doi: 10.1161/JAHA.120.018756. Epub 2021 Feb 6. J Am Heart Assoc. 2021. PMID: 33554615 Free PMC article.
Adverse Effects of Oseltamivir Phosphate Therapy on the Liver of LDLR-/- Mice Without Any Benefit on Atherosclerosis and Thrombosis.
Bocquet O, Wahart A, Sarazin T, Vincent E, Schneider C, Fougerat A, Gayral S, Henry A, Blaise S, Romier-Crouzet B, Boulagnon C, Jaisson S, Gillery P, Bennasroune A, Sartelet H, Laffargue M, Martiny L, Duca L, Maurice P. Bocquet O, et al. Among authors: fougerat a. J Cardiovasc Pharmacol. 2021 May 1;77(5):660-672. doi: 10.1097/FJC.0000000000001002. J Cardiovasc Pharmacol. 2021. PMID: 33760798
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: fougerat a. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism.
Huillet M, Lasserre F, Gratacap MP, Engelmann B, Bruse J, Polizzi A, Fougeray T, Martin CMP, Rives C, Fougerat A, Naylies C, Lippi Y, Garcia G, Rousseau-Bacquie E, Canlet C, Debrauwer L, Rolle-Kampczyk U, von Bergen M, Payrastre B, Boutet-Robinet E, Gamet-Payrastre L, Guillou H, Loiseau N, Ellero-Simatos S. Huillet M, et al. Among authors: fougerat a. JHEP Rep. 2023 Oct 13;6(1):100930. doi: 10.1016/j.jhepr.2023.100930. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38149074 Free PMC article.
41 results