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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.
Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD. Nuccitelli A, et al. Among authors: cozzi r. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593422 Free PMC article.
Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.
Necchi F, Nardi-Dei V, Biagini M, Assfalg M, Nuccitelli A, Cozzi R, Norais N, Telford JL, Rinaudo CD, Grandi G, Maione D. Necchi F, et al. Among authors: cozzi r. PLoS One. 2011;6(10):e25300. doi: 10.1371/journal.pone.0025300. Epub 2011 Oct 4. PLoS One. 2011. PMID: 21991306 Free PMC article.
Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus.
Nuccitelli A, Rinaudo CD, Brogioni B, Cozzi R, Ferrer-Navarro M, Yero D, Telford JL, Grandi G, Daura X, Zacharias M, Maione D. Nuccitelli A, et al. Among authors: cozzi r. PLoS Comput Biol. 2013;9(6):e1003115. doi: 10.1371/journal.pcbi.1003115. Epub 2013 Jun 27. PLoS Comput Biol. 2013. PMID: 23825940 Free PMC article.
208 results