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Cytoplasmic polyadenylation element binding protein deficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance.
Alexandrov IM, Ivshina M, Jung DY, Friedline R, Ko HJ, Xu M, O'Sullivan-Murphy B, Bortell R, Huang YT, Urano F, Kim JK, Richter JD. Alexandrov IM, et al. Among authors: bortell r. PLoS Genet. 2012 Jan;8(1):e1002457. doi: 10.1371/journal.pgen.1002457. Epub 2012 Jan 12. PLoS Genet. 2012. PMID: 22253608 Free PMC article.
Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.
Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Friedline RH, et al. Among authors: bortell r. FASEB J. 2016 Mar;30(3):1328-38. doi: 10.1096/fj.15-280610. Epub 2015 Dec 7. FASEB J. 2016. PMID: 26644351 Free PMC article.
A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells.
Jurczyk A, Pino SC, O'Sullivan-Murphy B, Addorio M, Lidstone EA, Diiorio P, Lipson KL, Standley C, Fogarty K, Lifshitz L, Urano F, Mordes JP, Greiner DL, Rossini AA, Bortell R. Jurczyk A, et al. Among authors: bortell r. PLoS One. 2010 Jul 27;5(7):e11812. doi: 10.1371/journal.pone.0011812. PLoS One. 2010. PMID: 20676397 Free PMC article.
Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin.
Jurczyk A, Diiorio P, Brostowin D, Leehy L, Yang C, Urano F, Harlan DM, Shultz LD, Greiner DL, Bortell R. Jurczyk A, et al. Among authors: bortell r. Diabetes Metab Syndr Obes. 2013 Dec 13;6:493-9. doi: 10.2147/DMSO.S53154. eCollection 2013. Diabetes Metab Syndr Obes. 2013. PMID: 24376359 Free PMC article.
84 results