Penning TM - Search Results

1

Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride.

Byrns MC, Mindnich R, Duan L, Penning TM. Byrns MC, et al. Among authors: penning tm. J Steroid Biochem Mol Biol. 2012 May;130(1-2):7-15. doi: 10.1016/j.jsbmb.2011.12.012. Epub 2012 Jan 12. J Steroid Biochem Mol Biol. 2012. PMID: 22265960 Free PMC article.

2

Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases.

Schlegel BP, Jez JM, Penning TM. Schlegel BP, et al. Among authors: penning tm. Biochemistry. 1998 Mar 10;37(10):3538-48. doi: 10.1021/bi9723055. Biochemistry. 1998. PMID: 9521675

3

Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine.

Schlegel BP, Ratnam K, Penning TM. Schlegel BP, et al. Among authors: penning tm. Biochemistry. 1998 Aug 4;37(31):11003-11. doi: 10.1021/bi980475r. Biochemistry. 1998. PMID: 9692994

4

The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3 alpha-hydroxysteroid dehydrogenase, a representative aldo-keto reductase.

Ratnam K, Ma H, Penning TM. Ratnam K, et al. Among authors: penning tm. Biochemistry. 1999 Jun 15;38(24):7856-64. doi: 10.1021/bi982838t. Biochemistry. 1999. PMID: 10387026

5

Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase.

Penning TM. Penning TM. J Steroid Biochem Mol Biol. 1999 Apr-Jun;69(1-6):211-25. doi: 10.1016/s0960-0760(99)00038-2. J Steroid Biochem Mol Biol. 1999. PMID: 10418995 Review.

6

Genomic structure of rat 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (3alpha-HSD/DD, AKR1C9).

Lin HK, Hung CF, Moore M, Penning TM. Lin HK, et al. Among authors: penning tm. J Steroid Biochem Mol Biol. 1999 Nov;71(1-2):29-39. doi: 10.1016/s0960-0760(99)00122-3. J Steroid Biochem Mol Biol. 1999. PMID: 10619355 Free article.

7

Engineering steroid hormone specificity into aldo-keto reductases.

Penning TM, Ma H, Jez JM. Penning TM, et al. Chem Biol Interact. 2001 Jan 30;130-132(1-3):659-71. doi: 10.1016/s0009-2797(00)00257-x. Chem Biol Interact. 2001. PMID: 11306084

8

Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism.

Jin Y, Penning TM. Jin Y, et al. Among authors: penning tm. Best Pract Res Clin Endocrinol Metab. 2001 Mar;15(1):79-94. doi: 10.1053/beem.2001.0120. Best Pract Res Clin Endocrinol Metab. 2001. PMID: 11469812 Review.

9

Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.

Palackal NT, Lee SH, Harvey RG, Blair IA, Penning TM. Palackal NT, et al. Among authors: penning tm. J Biol Chem. 2002 Jul 5;277(27):24799-808. doi: 10.1074/jbc.M112424200. Epub 2002 Apr 26. J Biol Chem. 2002. PMID: 11978787 Free article.

10

Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells.

Rizner TL, Lin HK, Penning TM. Rizner TL, et al. Among authors: penning tm. Chem Biol Interact. 2003 Feb 1;143-144:401-9. doi: 10.1016/s0009-2797(02)00179-5. Chem Biol Interact. 2003. PMID: 12604227

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,890 results

Search Page

Filters