Noblin DJ - Search Results

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Identification of hydrophobic tags for the degradation of stabilized proteins.

Tae HS, Sundberg TB, Neklesa TK, Noblin DJ, Gustafson JL, Roth AG, Raina K, Crews CM. Tae HS, et al. Among authors: noblin dj. Chembiochem. 2012 Mar 5;13(4):538-41. doi: 10.1002/cbic.201100793. Epub 2012 Jan 23. Chembiochem. 2012. PMID: 22271667 Free PMC article.

A bidirectional system for the dynamic small molecule control of intracellular fusion proteins.

Neklesa TK, Noblin DJ, Kuzin AP, Lew S, Seetharaman J, Acton TB, Kornhaber GJ, Xiao R, Montelione GT, Tong L, Crews CM. Neklesa TK, et al. Among authors: noblin dj. ACS Chem Biol. 2013 Oct 18;8(10):2293-2300. doi: 10.1021/cb400569k. Epub 2013 Aug 26. ACS Chem Biol. 2013. PMID: 23978068 Free PMC article.

Targeted protein destabilization reveals an estrogen-mediated ER stress response.

Raina K, Noblin DJ, Serebrenik YV, Adams A, Zhao C, Crews CM. Raina K, et al. Among authors: noblin dj. Nat Chem Biol. 2014 Nov;10(11):957-62. doi: 10.1038/nchembio.1638. Epub 2014 Sep 21. Nat Chem Biol. 2014. PMID: 25242550 Free PMC article.

A HaloTag-based small molecule microarray screening methodology with increased sensitivity and multiplex capabilities.

Noblin DJ, Page CM, Tae HS, Gareiss PC, Schneekloth JS, Crews CM. Noblin DJ, et al. ACS Chem Biol. 2012 Dec 21;7(12):2055-63. doi: 10.1021/cb300453k. Epub 2012 Oct 11. ACS Chem Biol. 2012. PMID: 23013033 Free PMC article.

Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction.

Buckley DL, Van Molle I, Gareiss PC, Tae HS, Michel J, Noblin DJ, Jorgensen WL, Ciulli A, Crews CM. Buckley DL, et al. Among authors: noblin dj. J Am Chem Soc. 2012 Mar 14;134(10):4465-8. doi: 10.1021/ja209924v. Epub 2012 Feb 27. J Am Chem Soc. 2012. PMID: 22369643 Free PMC article.

Development of a high-throughput calcium flux assay for identification of all ligand types including positive, negative, and silent allosteric modulators for G protein-coupled receptors.

Noblin DJ, Bertekap RL Jr, Burford NT, Hendricson A, Zhang L, Knox R, Banks M, O'Connell J, Alt A. Noblin DJ, et al. Assay Drug Dev Technol. 2012 Oct;10(5):457-67. doi: 10.1089/adt.2011.443. Epub 2012 Jun 29. Assay Drug Dev Technol. 2012. PMID: 22746835

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