Chambers RC - Search Results

1

PAR-1-dependent and PAR-independent pro-inflammatory signaling in human lung fibroblasts exposed to thrombin.

Ortiz-Stern A, Deng X, Smoktunowicz N, Mercer PF, Chambers RC. Ortiz-Stern A, et al. Among authors: chambers rc. J Cell Physiol. 2012 Nov;227(11):3575-84. doi: 10.1002/jcp.24061. J Cell Physiol. 2012. PMID: 22278285

2

Thrombin stimulates smooth muscle cell procollagen synthesis and mRNA levels via a PAR-1 mediated mechanism.

Dabbagh K, Laurent GJ, McAnulty RJ, Chambers RC. Dabbagh K, et al. Among authors: chambers rc. Thromb Haemost. 1998 Feb;79(2):405-9. Thromb Haemost. 1998. PMID: 9493599

3

Thrombin.

Goldsack NR, Chambers RC, Dabbagh K, Laurent GJ. Goldsack NR, et al. Among authors: chambers rc. Int J Biochem Cell Biol. 1998 Jun;30(6):641-6. doi: 10.1016/s1357-2725(98)00011-9. Int J Biochem Cell Biol. 1998. PMID: 9695019 Review.

4

Alpha-1-antitrypsin stimulates fibroblast proliferation and procollagen production and activates classical MAP kinase signalling pathways.

Dabbagh K, Laurent GJ, Shock A, Leoni P, Papakrivopoulou J, Chambers RC. Dabbagh K, et al. Among authors: chambers rc. J Cell Physiol. 2001 Jan;186(1):73-81. doi: 10.1002/1097-4652(200101)186:1<73::AID-JCP1002>3.0.CO;2-Q. J Cell Physiol. 2001. PMID: 11147816

5

Role of thrombin and its major cellular receptor, protease-activated receptor-1, in pulmonary fibrosis.

Howell DC, Laurent GJ, Chambers RC. Howell DC, et al. Among authors: chambers rc. Biochem Soc Trans. 2002 Apr;30(2):211-6. Biochem Soc Trans. 2002. PMID: 12023853 Review.

6

Angiotensin II and the fibroproliferative response to acute lung injury.

Marshall RP, Gohlke P, Chambers RC, Howell DC, Bottoms SE, Unger T, McAnulty RJ, Laurent GJ. Marshall RP, et al. Among authors: chambers rc. Am J Physiol Lung Cell Mol Physiol. 2004 Jan;286(1):L156-64. doi: 10.1152/ajplung.00313.2002. Epub 2003 May 16. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 12754187 Free article.

7

Activation of proteinase-activated receptor-2 in mesothelial cells induces pleural inflammation.

Lee YC, Knight DA, Lane KB, Cheng DS, Koay MA, Teixeira LR, Nesbitt JC, Chambers RC, Thompson PJ, Light RW. Lee YC, et al. Among authors: chambers rc. Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L734-40. doi: 10.1152/ajplung.00173.2004. Epub 2004 Dec 10. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15591415 Free article.

8

Signaling pathways involved in proteinase-activated receptor1-induced proinflammatory and profibrotic mediator release following lung injury.

Mercer PF, Deng X, Chambers RC. Mercer PF, et al. Among authors: chambers rc. Ann N Y Acad Sci. 2007 Jan;1096:86-8. doi: 10.1196/annals.1397.073. Ann N Y Acad Sci. 2007. PMID: 17405919

9

Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?

Chambers RC. Chambers RC. Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S367-78. doi: 10.1038/sj.bjp.0707603. Epub 2008 Jan 28. Br J Pharmacol. 2008. PMID: 18223674 Free PMC article. Review.

10

Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways.

Deng X, Mercer PF, Scotton CJ, Gilchrist A, Chambers RC. Deng X, et al. Among authors: chambers rc. Mol Biol Cell. 2008 Jun;19(6):2520-33. doi: 10.1091/mbc.e07-07-0720. Epub 2008 Mar 19. Mol Biol Cell. 2008. PMID: 18353977 Free PMC article.

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