Goulding CW - Search Results

1

Characterization of heme ligation properties of Rv0203, a secreted heme binding protein involved in Mycobacterium tuberculosis heme uptake.

Owens CP, Du J, Dawson JH, Goulding CW. Owens CP, et al. Among authors: goulding cw. Biochemistry. 2012 Feb 21;51(7):1518-31. doi: 10.1021/bi2018305. Epub 2012 Feb 8. Biochemistry. 2012. PMID: 22283334 Free PMC article.

2

Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis.

Chim N, Iniguez A, Nguyen TQ, Goulding CW. Chim N, et al. Among authors: goulding cw. J Mol Biol. 2010 Jan 22;395(3):595-608. doi: 10.1016/j.jmb.2009.11.025. Epub 2009 Nov 14. J Mol Biol. 2010. PMID: 19917297 Free PMC article.

3

Discovery and characterization of a unique mycobacterial heme acquisition system.

Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. Tullius MV, et al. Among authors: goulding cw. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5051-6. doi: 10.1073/pnas.1009516108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383189 Free PMC article.

4

Differential function of lip residues in the mechanism and biology of an anthrax hemophore.

Ekworomadu MT, Poor CB, Owens CP, Balderas MA, Fabian M, Olson JS, Murphy F, Bakkalbasi E, Honsa ES, He C, Goulding CW, Maresso AW. Ekworomadu MT, et al. Among authors: goulding cw. PLoS Pathog. 2012;8(3):e1002559. doi: 10.1371/journal.ppat.1002559. Epub 2012 Mar 8. PLoS Pathog. 2012. PMID: 22412371 Free PMC article.

5

The near-iron transporter (NEAT) domains of the anthrax hemophore IsdX2 require a critical glutamine to extract heme from methemoglobin.

Honsa ES, Owens CP, Goulding CW, Maresso AW. Honsa ES, et al. Among authors: goulding cw. J Biol Chem. 2013 Mar 22;288(12):8479-8490. doi: 10.1074/jbc.M112.430009. Epub 2013 Jan 30. J Biol Chem. 2013. PMID: 23364793 Free PMC article.

6

A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO.

Nambu S, Matsui T, Goulding CW, Takahashi S, Ikeda-Saito M. Nambu S, et al. Among authors: goulding cw. J Biol Chem. 2013 Apr 5;288(14):10101-10109. doi: 10.1074/jbc.M112.448399. Epub 2013 Feb 18. J Biol Chem. 2013. PMID: 23420845 Free PMC article.

7

The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11.

Owens CP, Chim N, Graves AB, Harmston CA, Iniguez A, Contreras H, Liptak MD, Goulding CW. Owens CP, et al. Among authors: goulding cw. J Biol Chem. 2013 Jul 26;288(30):21714-28. doi: 10.1074/jbc.M113.453076. Epub 2013 Jun 11. J Biol Chem. 2013. PMID: 23760277 Free PMC article.

8

Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.

Owens CP, Chim N, Goulding CW. Owens CP, et al. Among authors: goulding cw. Future Med Chem. 2013 Aug;5(12):1391-403. doi: 10.4155/fmc.13.109. Future Med Chem. 2013. PMID: 23919550 Free PMC article.

9

Insights into redox sensing metalloproteins in Mycobacterium tuberculosis.

Chim N, Johnson PM, Goulding CW. Chim N, et al. Among authors: goulding cw. J Inorg Biochem. 2014 Apr;133:118-26. doi: 10.1016/j.jinorgbio.2013.11.003. Epub 2013 Nov 15. J Inorg Biochem. 2014. PMID: 24314844 Free PMC article. Review.

10

Heme uptake in bacterial pathogens.

Contreras H, Chim N, Credali A, Goulding CW. Contreras H, et al. Among authors: goulding cw. Curr Opin Chem Biol. 2014 Apr;19:34-41. doi: 10.1016/j.cbpa.2013.12.014. Epub 2014 Jan 4. Curr Opin Chem Biol. 2014. PMID: 24780277 Free PMC article. Review.

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