Dimova NV - Search Results

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APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1.

Dimova NV, Hathaway NA, Lee BH, Kirkpatrick DS, Berkowitz ML, Gygi SP, Finley D, King RW. Dimova NV, et al. Nat Cell Biol. 2012 Jan 29;14(2):168-76. doi: 10.1038/ncb2425. Nat Cell Biol. 2012. PMID: 22286100 Free PMC article.

Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Lee BH, et al. Nature. 2010 Sep 9;467(7312):179-84. doi: 10.1038/nature09299. Nature. 2010. PMID: 20829789 Free PMC article.

Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage.

Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW. Zeng X, et al. Cancer Cell. 2010 Oct 19;18(4):382-95. doi: 10.1016/j.ccr.2010.08.010. Cancer Cell. 2010. PMID: 20951947 Free PMC article.

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.

Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, King RW. Sackton KL, et al. Nature. 2014 Oct 30;514(7524):646-9. doi: 10.1038/nature13660. Epub 2014 Aug 24. Nature. 2014. PMID: 25156254 Free PMC article.

The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.

Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. Lim HJ, et al. Among authors: dimova nv. Mol Cell Biol. 2013 Nov;33(21):4166-80. doi: 10.1128/MCB.00689-13. Epub 2013 Aug 26. Mol Cell Biol. 2013. PMID: 23979597 Free PMC article.

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