Kemper JK - Search Results

1

Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.

Purushotham A, Xu Q, Lu J, Foley JF, Yan X, Kim DH, Kemper JK, Li X. Purushotham A, et al. Among authors: kemper jk. Mol Cell Biol. 2012 Apr;32(7):1226-36. doi: 10.1128/MCB.05988-11. Epub 2012 Jan 30. Mol Cell Biol. 2012. PMID: 22290433 Free PMC article.

2

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha.

Goodwin B, Watson MA, Kim H, Miao J, Kemper JK, Kliewer SA. Goodwin B, et al. Among authors: kemper jk. Mol Endocrinol. 2003 Mar;17(3):386-94. doi: 10.1210/me.2002-0246. Epub 2002 Dec 12. Mol Endocrinol. 2003. PMID: 12554795

3

Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.

Miao J, Fang S, Lee J, Comstock C, Knudsen KE, Kemper JK. Miao J, et al. Among authors: kemper jk. Mol Cell Biol. 2009 Dec;29(23):6170-81. doi: 10.1128/MCB.00825-09. Epub 2009 Oct 5. Mol Cell Biol. 2009. PMID: 19805516 Free PMC article.

4

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.

Ponugoti B, Kim DH, Xiao Z, Smith Z, Miao J, Zang M, Wu SY, Chiang CM, Veenstra TD, Kemper JK. Ponugoti B, et al. Among authors: kemper jk. J Biol Chem. 2010 Oct 29;285(44):33959-70. doi: 10.1074/jbc.M110.122978. Epub 2010 Sep 3. J Biol Chem. 2010. PMID: 20817729 Free PMC article.

5

Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner.

Kanamaluru D, Xiao Z, Fang S, Choi SE, Kim DH, Veenstra TD, Kemper JK. Kanamaluru D, et al. Among authors: kemper jk. Mol Cell Biol. 2011 Apr;31(7):1540-50. doi: 10.1128/MCB.01212-10. Epub 2011 Jan 24. Mol Cell Biol. 2011. PMID: 21262773 Free PMC article.

6

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.

Fu T, Choi SE, Kim DH, Seok S, Suino-Powell KM, Xu HE, Kemper JK. Fu T, et al. Among authors: kemper jk. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16137-42. doi: 10.1073/pnas.1205951109. Epub 2012 Sep 17. Proc Natl Acad Sci U S A. 2012. PMID: 22988100 Free PMC article.

7

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK. Choi SE, et al. Among authors: kemper b, kemper jk. Aging Cell. 2013 Dec;12(6):1062-72. doi: 10.1111/acel.12135. Epub 2013 Aug 11. Aging Cell. 2013. PMID: 23834033 Free PMC article.

8

MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function.

Fu T, Seok S, Choi S, Huang Z, Suino-Powell K, Xu HE, Kemper B, Kemper JK. Fu T, et al. Among authors: kemper b, kemper jk. Mol Cell Biol. 2014 Nov 15;34(22):4130-42. doi: 10.1128/MCB.00596-14. Epub 2014 Sep 2. Mol Cell Biol. 2014. PMID: 25182532 Free PMC article.

9

A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity.

Kim DH, Xiao Z, Kwon S, Sun X, Ryerson D, Tkac D, Ma P, Wu SY, Chiang CM, Zhou E, Xu HE, Palvimo JJ, Chen LF, Kemper B, Kemper JK. Kim DH, et al. Among authors: kemper b, kemper jk. EMBO J. 2015 Jan 13;34(2):184-99. doi: 10.15252/embj.201489527. Epub 2014 Nov 25. EMBO J. 2015. PMID: 25425577 Free PMC article.

10

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.

Fu T, Kim YC, Byun S, Kim DH, Seok S, Suino-Powell K, Xu HE, Kemper B, Kemper JK. Fu T, et al. Among authors: kemper b, kemper jk. Mol Endocrinol. 2016 Jan;30(1):92-103. doi: 10.1210/me.2015-1226. Epub 2015 Oct 27. Mol Endocrinol. 2016. PMID: 26505219 Free PMC article.

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