Aklillu E - Search Results

1

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes.

Hatta FH, Teh LK, Helldén A, Hellgren KE, Roh HK, Salleh MZ, Aklillu E, Bertilsson L. Hatta FH, et al. Among authors: aklillu e. Eur J Clin Pharmacol. 2012 Jul;68(7):1033-42. doi: 10.1007/s00228-012-1210-0. Epub 2012 Feb 1. Eur J Clin Pharmacol. 2012. PMID: 22294058

2

Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.

Aklillu E, Persson I, Bertilsson L, Johansson I, Rodrigues F, Ingelman-Sundberg M. Aklillu E, et al. J Pharmacol Exp Ther. 1996 Jul;278(1):441-6. J Pharmacol Exp Ther. 1996. PMID: 8764380

3

S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians.

Persson I, Aklillu E, Rodrigues F, Bertilsson L, Ingelman-Sundberg M. Persson I, et al. Among authors: aklillu e. Pharmacogenetics. 1996 Dec;6(6):521-6. doi: 10.1097/00008571-199612000-00005. Pharmacogenetics. 1996. PMID: 9014201

4

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

Scordo MG, Aklillu E, Yasar U, Dahl ML, Spina E, Ingelman-Sundberg M. Scordo MG, et al. Among authors: aklillu e. Br J Clin Pharmacol. 2001 Oct;52(4):447-50. doi: 10.1046/j.0306-5251.2001.01460.x. Br J Clin Pharmacol. 2001. PMID: 11678789 Free PMC article.

5

Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population.

Aklillu E, Oscarson M, Hidestrand M, Leidvik B, Otter C, Ingelman-Sundberg M. Aklillu E, et al. Mol Pharmacol. 2002 Mar;61(3):586-94. doi: 10.1124/mol.61.3.586. Mol Pharmacol. 2002. PMID: 11854439

6

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden.

Aklillu E, Herrlin K, Gustafsson LL, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Pharmacogenetics. 2002 Jul;12(5):375-83. doi: 10.1097/00008571-200207000-00005. Pharmacogenetics. 2002. PMID: 12142727

7

Analysis of CYP2C9*5 in Caucasian, Oriental and black-African populations.

Yasar U, Aklillu E, Canaparo R, Sandberg M, Sayi J, Roh HK, Wennerholm A. Yasar U, et al. Among authors: aklillu e. Eur J Clin Pharmacol. 2002 Nov;58(8):555-8. doi: 10.1007/s00228-002-0518-6. Epub 2002 Nov 1. Eur J Clin Pharmacol. 2002. PMID: 12451434

8

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

Aklillu E, Carrillo JA, Makonnen E, Hellman K, Pitarque M, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Mol Pharmacol. 2003 Sep;64(3):659-69. doi: 10.1124/mol.64.3.659. Mol Pharmacol. 2003. PMID: 12920202

9

Xanthine oxidase activity is influenced by environmental factors in Ethiopians.

Aklillu E, Carrillo JA, Makonnen E, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Eur J Clin Pharmacol. 2003 Oct;59(7):533-6. doi: 10.1007/s00228-003-0653-8. Epub 2003 Aug 21. Eur J Clin Pharmacol. 2003. PMID: 12937875

10

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.

Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M. Sim SC, et al. Among authors: aklillu e. Clin Pharmacol Ther. 2006 Jan;79(1):103-13. doi: 10.1016/j.clpt.2005.10.002. Clin Pharmacol Ther. 2006. PMID: 16413245

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