Curran CP - Search Results

1

Effect of vitamin C deficiency during postnatal development on adult behavior: functional phenotype of Gulo-/- knockout mice.

Chen Y, Curran CP, Nebert DW, Patel KV, Williams MT, Vorhees CV. Chen Y, et al. Among authors: curran cp. Genes Brain Behav. 2012 Apr;11(3):269-77. doi: 10.1111/j.1601-183X.2011.00762.x. Epub 2012 Feb 2. Genes Brain Behav. 2012. PMID: 22296218 Free PMC article.

2

Effect of chronic glutathione deficiency on the behavioral phenotype of Gclm-/- knockout mice.

Chen Y, Curran CP, Nebert DW, Patel KV, Williams MT, Vorhees CV. Chen Y, et al. Among authors: curran cp. Neurotoxicol Teratol. 2012 Jul;34(4):450-7. doi: 10.1016/j.ntt.2012.04.009. Epub 2012 May 10. Neurotoxicol Teratol. 2012. PMID: 22580179 Free PMC article.

3

Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

Derkenne S, Curran CP, Shertzer HG, Dalton TP, Dragin N, Nebert DW. Derkenne S, et al. Among authors: curran cp. Pharmacogenet Genomics. 2005 Jul;15(7):503-11. doi: 10.1097/01.fpc.0000167326.00411.50. Pharmacogenet Genomics. 2005. PMID: 15970798

4

Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl.

Curran CP, Miller KA, Dalton TP, Vorhees CV, Miller ML, Shertzer HG, Nebert DW. Curran CP, et al. Toxicol Sci. 2006 Feb;89(2):454-64. doi: 10.1093/toxsci/kfj048. Epub 2005 Nov 16. Toxicol Sci. 2006. PMID: 16291824

5

In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.

Curran CP, Vorhees CV, Williams MT, Genter MB, Miller ML, Nebert DW. Curran CP, et al. Toxicol Sci. 2011 Jan;119(1):189-208. doi: 10.1093/toxsci/kfq314. Epub 2010 Oct 20. Toxicol Sci. 2011. PMID: 20961953 Free PMC article.

6

In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes.

Curran CP, Nebert DW, Genter MB, Patel KV, Schaefer TL, Skelton MR, Williams MT, Vorhees CV. Curran CP, et al. Environ Health Perspect. 2011 Sep;119(9):1286-93. doi: 10.1289/ehp.1002965. Epub 2011 May 13. Environ Health Perspect. 2011. PMID: 21571617 Free PMC article.

We previously characterized specific differences in PCB congener pharmacokinetics and toxicity, comparing high-affinity-AHR Cyp1a2 wild-type [Ahrb1_Cyp1a2(+/+)], poor-affinity-AHR Cyp1a2 wild-type [Ahrd_Cyp1a2(+/+)], and high-affinity-AHR Cyp1a2 knockout [Ahrb1_Cyp1a2(-/-)] mouse …

We previously characterized specific differences in PCB congener pharmacokinetics and toxicity, comparing high-affinity-AHR Cyp1a2 wild-type …

7

7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

Shertzer HG, Genter MB, Talaska G, Curran CP, Nebert DW, Dalton TP. Shertzer HG, et al. Among authors: curran cp. Carcinogenesis. 2007 Jun;28(6):1371-8. doi: 10.1093/carcin/bgl244. Epub 2006 Dec 13. Carcinogenesis. 2007. PMID: 17166882

8

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: curran cp. Mol Pharmacol. 2006 Apr;69(4):1103-14. doi: 10.1124/mol.105.021501. Epub 2005 Dec 23. Mol Pharmacol. 2006. PMID: 16377763

9

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.

Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: curran cp. Mol Pharmacol. 2004 May;65(5):1225-37. doi: 10.1124/mol.65.5.1225. Mol Pharmacol. 2004. PMID: 15102951

10

Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls.

Colter BT, Garber HF, Fleming SM, Fowler JP, Harding GD, Hooven MK, Howes AA, Infante SK, Lang AL, MacDougall MC, Stegman M, Taylor KR, Curran CP. Colter BT, et al. Among authors: curran cp. Neurotoxicology. 2018 Mar;65:125-134. doi: 10.1016/j.neuro.2018.01.008. Neurotoxicology. 2018. PMID: 29409959 Free PMC article.

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