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Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites.
Wort SJ, Ito M, Chou PC, Mc Master SK, Badiger R, Jazrawi E, de Souza P, Evans TW, Mitchell JA, Pinhu L, Ito K, Adcock IM. Wort SJ, et al. Among authors: adcock im. J Biol Chem. 2009 Sep 4;284(36):24297-305. doi: 10.1074/jbc.M109.032524. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592490 Free PMC article.
Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats.
Price LC, Montani D, Tcherakian C, Dorfmüller P, Souza R, Gambaryan N, Chaumais MC, Shao DM, Simonneau G, Howard LS, Adcock IM, Wort SJ, Humbert M, Perros F. Price LC, et al. Among authors: adcock im. Eur Respir J. 2011 Apr;37(4):813-22. doi: 10.1183/09031936.00028310. Epub 2010 Aug 6. Eur Respir J. 2011. PMID: 20693255 Free article.
Cigarette smoke induced airway inflammation is independent of NF-κB signalling.
Rastrick JM, Stevenson CS, Eltom S, Grace M, Davies M, Kilty I, Evans SM, Pasparakis M, Catley MC, Lawrence T, Adcock IM, Belvisi MG, Birrell MA. Rastrick JM, et al. Among authors: adcock im. PLoS One. 2013;8(1):e54128. doi: 10.1371/journal.pone.0054128. Epub 2013 Jan 22. PLoS One. 2013. PMID: 23349803 Free PMC article.
Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.
Price LC, Caramori G, Perros F, Meng C, Gambaryan N, Dorfmuller P, Montani D, Casolari P, Zhu J, Dimopoulos K, Shao D, Girerd B, Mumby S, Proudfoot A, Griffiths M, Papi A, Humbert M, Adcock IM, Wort SJ. Price LC, et al. Among authors: adcock im. PLoS One. 2013 Oct 4;8(10):e75415. doi: 10.1371/journal.pone.0075415. eCollection 2013. PLoS One. 2013. PMID: 24124488 Free PMC article.
Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial hypertension.
Shao D, Perros F, Caramori G, Meng C, Dormuller P, Chou PC, Church C, Papi A, Casolari P, Welsh D, Peacock A, Humbert M, Adcock IM, Wort SJ. Shao D, et al. Among authors: adcock im. Biochem Biophys Res Commun. 2014 Aug 15;451(1):8-14. doi: 10.1016/j.bbrc.2014.06.111. Epub 2014 Jul 5. Biochem Biophys Res Commun. 2014. PMID: 25003325 Free article.
Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
Price LC, Shao D, Meng C, Perros F, Garfield BE, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock IM, Wort SJ. Price LC, et al. Among authors: adcock im. Respir Res. 2015 Sep 18;16(1):114. doi: 10.1186/s12931-015-0262-y. Respir Res. 2015. PMID: 26382031 Free PMC article.
592 results