Rodriguez R - Search Results

1

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.

Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Rodriguez R, et al. Nat Chem Biol. 2012 Feb 5;8(3):301-10. doi: 10.1038/nchembio.780. Nat Chem Biol. 2012. PMID: 22306580 Free PMC article.

2

Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands.

Jantos K, Rodriguez R, Ladame S, Shirude PS, Balasubramanian S. Jantos K, et al. Among authors: rodriguez r. J Am Chem Soc. 2006 Oct 25;128(42):13662-3. doi: 10.1021/ja064713e. J Am Chem Soc. 2006. PMID: 17044674 Free PMC article.

3

Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands.

Gonçalves DP, Rodriguez R, Balasubramanian S, Sanders JK. Gonçalves DP, et al. Among authors: rodriguez r. Chem Commun (Camb). 2006 Dec 7;(45):4685-7. doi: 10.1039/b611731g. Epub 2006 Sep 27. Chem Commun (Camb). 2006. PMID: 17109036 Free PMC article.

4

Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction.

Rodriguez R, Pantoş GD, Gonçalves DP, Sanders JK, Balasubramanian S. Rodriguez R, et al. Angew Chem Int Ed Engl. 2007;46(28):5405-7. doi: 10.1002/anie.200605075. Angew Chem Int Ed Engl. 2007. PMID: 17562537 Free PMC article. No abstract available.

5

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression.

Bejugam M, Sewitz S, Shirude PS, Rodriguez R, Shahid R, Balasubramanian S. Bejugam M, et al. Among authors: rodriguez r. J Am Chem Soc. 2007 Oct 31;129(43):12926-7. doi: 10.1021/ja075881p. Epub 2007 Oct 5. J Am Chem Soc. 2007. PMID: 17918848 Free PMC article. No abstract available.

6

Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry.

Bugaut A, Jantos K, Wietor JL, Rodriguez R, Sanders JK, Balasubramanian S. Bugaut A, et al. Among authors: rodriguez r. Angew Chem Int Ed Engl. 2008;47(14):2677-80. doi: 10.1002/anie.200705589. Angew Chem Int Ed Engl. 2008. PMID: 18300215 Free PMC article. No abstract available.

7

Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition.

Waller ZA, Shirude PS, Rodriguez R, Balasubramanian S. Waller ZA, et al. Among authors: rodriguez r. Chem Commun (Camb). 2008 Mar 28;(12):1467-9. doi: 10.1039/b718854d. Epub 2008 Jan 29. Chem Commun (Camb). 2008. PMID: 18338058 Free PMC article.

8

Selective recognition of a DNA G-quadruplex by an engineered antibody.

Fernando H, Rodriguez R, Balasubramanian S. Fernando H, et al. Among authors: rodriguez r. Biochemistry. 2008 Sep 9;47(36):9365-71. doi: 10.1021/bi800983u. Epub 2008 Aug 15. Biochemistry. 2008. PMID: 18702511 Free PMC article.

9

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.

Rodriguez R, Müller S, Yeoman JA, Trentesaux C, Riou JF, Balasubramanian S. Rodriguez R, et al. J Am Chem Soc. 2008 Nov 26;130(47):15758-9. doi: 10.1021/ja805615w. J Am Chem Soc. 2008. PMID: 18975896 Free PMC article.

10

Controlled-folding of a small molecule modulates DNA G-quadruplex recognition.

Müller S, Pantoş GD, Rodriguez R, Balasubramanian S. Müller S, et al. Among authors: rodriguez r. Chem Commun (Camb). 2009 Jan 7;(1):80-2. doi: 10.1039/b816861j. Epub 2008 Nov 12. Chem Commun (Camb). 2009. PMID: 19082005 Free PMC article.

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