Jove R - Search Results

1

Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.

Yang F, Jove V, Chang S, Hedvat M, Liu L, Buettner R, Tian Y, Scuto A, Wen W, Yip ML, Van Meter T, Yen Y, Jove R. Yang F, et al. Among authors: jove r, jove v. Cancer Biol Ther. 2012 Apr;13(6):349-57. doi: 10.4161/cbt.19239. Epub 2012 Apr 1. Cancer Biol Ther. 2012. PMID: 22313636 Free PMC article.

2

6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.

Liu L, Nam S, Tian Y, Yang F, Wu J, Wang Y, Scuto A, Polychronopoulos P, Magiatis P, Skaltsounis L, Jove R. Liu L, et al. Among authors: jove r. Cancer Res. 2011 Jun 1;71(11):3972-9. doi: 10.1158/0008-5472.CAN-10-3852. Epub 2011 May 24. Cancer Res. 2011. PMID: 21610112 Free PMC article.

3

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.

Yang F, Jove V, Buettner R, Xin H, Wu J, Wang Y, Nam S, Xu Y, Ara T, DeClerck YA, Seeger R, Yu H, Jove R. Yang F, et al. Among authors: jove r, jove v. Cancer Biol Ther. 2012 May;13(7):534-41. doi: 10.4161/cbt.19603. Epub 2012 May 1. Cancer Biol Ther. 2012. PMID: 22406995 Free article.

4

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling.

Liu L, Kritsanida M, Magiatis P, Gaboriaud N, Wang Y, Wu J, Buettner R, Yang F, Nam S, Skaltsounis L, Jove R. Liu L, et al. Among authors: jove r. Cancer Biol Ther. 2012 Nov;13(13):1255-61. doi: 10.4161/cbt.21781. Epub 2012 Aug 16. Cancer Biol Ther. 2012. PMID: 22895078 Free PMC article.

5

Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.

Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R. Tian Y, et al. Among authors: jove r. PLoS One. 2012;7(11):e49306. doi: 10.1371/journal.pone.0049306. Epub 2012 Nov 16. PLoS One. 2012. PMID: 23166634 Free PMC article.

6

A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling.

Yang F, Nam S, Zhao R, Tian Y, Liu L, Horne DA, Jove R. Yang F, et al. Among authors: jove r. Cancer Biol Ther. 2013 Nov;14(11):1024-31. doi: 10.4161/cbt.26045. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025361 Free PMC article.

7

MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells.

Liu L, Gaboriaud N, Vougogianopoulou K, Tian Y, Wu J, Wen W, Skaltsounis L, Jove R. Liu L, et al. Among authors: jove r. Cancer Biol Ther. 2014 Feb;15(2):178-84. doi: 10.4161/cbt.26721. Epub 2013 Nov 1. Cancer Biol Ther. 2014. PMID: 24100507 Free PMC article.

8

Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer.

Wen W, Wu J, Liu L, Tian Y, Buettner R, Hsieh MY, Horne D, Dellinger TH, Han ES, Jove R, Yim JH. Wen W, et al. Among authors: jove r. Mol Cancer. 2015 May 1;14:100. doi: 10.1186/s12943-015-0366-5. Mol Cancer. 2015. PMID: 25928246 Free PMC article.

9

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.

Yang F, Van Meter TE, Buettner R, Hedvat M, Liang W, Kowolik CM, Mepani N, Mirosevich J, Nam S, Chen MY, Tye G, Kirschbaum M, Jove R. Yang F, et al. Among authors: jove r. Mol Cancer Ther. 2008 Nov;7(11):3519-26. doi: 10.1158/1535-7163.MCT-08-0138. Mol Cancer Ther. 2008. PMID: 19001435 Free PMC article.

10

Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.

Yang F, Brown C, Buettner R, Hedvat M, Starr R, Scuto A, Schroeder A, Jensen M, Jove R. Yang F, et al. Among authors: jove r. Mol Cancer Ther. 2010 Apr;9(4):953-62. doi: 10.1158/1535-7163.MCT-09-0947. Epub 2010 Apr 6. Mol Cancer Ther. 2010. PMID: 20371721 Free PMC article.

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