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Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.
Yang F, Jove V, Chang S, Hedvat M, Liu L, Buettner R, Tian Y, Scuto A, Wen W, Yip ML, Van Meter T, Yen Y, Jove R. Yang F, et al. Among authors: wen w. Cancer Biol Ther. 2012 Apr;13(6):349-57. doi: 10.4161/cbt.19239. Epub 2012 Apr 1. Cancer Biol Ther. 2012. PMID: 22313636 Free PMC article.
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R. Nam S, et al. Among authors: wen w. Mol Oncol. 2013 Jun;7(3):369-78. doi: 10.1016/j.molonc.2012.10.013. Epub 2012 Nov 16. Mol Oncol. 2013. PMID: 23206899 Free PMC article.
3,231 results