Ozawa T - Search Results

1

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response.

Szerlip NJ, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, Ozawa T, Holland EC, Huse JT, Jhanwar S, Leversha MA, Mikkelsen T, Brennan CW. Szerlip NJ, et al. Among authors: ozawa t. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3041-6. doi: 10.1073/pnas.1114033109. Epub 2012 Feb 8. Proc Natl Acad Sci U S A. 2012. PMID: 22323597 Free PMC article.

2

Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations.

Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, Holland E. Brennan C, et al. Among authors: ozawa t. PLoS One. 2009 Nov 13;4(11):e7752. doi: 10.1371/journal.pone.0007752. PLoS One. 2009. PMID: 19915670 Free PMC article.

3

miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis.

Silber J, Jacobsen A, Ozawa T, Harinath G, Pedraza A, Sander C, Holland EC, Huse JT. Silber J, et al. Among authors: ozawa t. PLoS One. 2012;7(3):e33844. doi: 10.1371/journal.pone.0033844. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479456 Free PMC article.

4

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.

Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. Ozawa T, et al. Genes Dev. 2010 Oct 1;24(19):2205-18. doi: 10.1101/gad.1972310. Genes Dev. 2010. PMID: 20889717 Free PMC article.

5

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.

Ozawa T, Riester M, Cheng YK, Huse JT, Squatrito M, Helmy K, Charles N, Michor F, Holland EC. Ozawa T, et al. Cancer Cell. 2014 Aug 11;26(2):288-300. doi: 10.1016/j.ccr.2014.06.005. Cancer Cell. 2014. PMID: 25117714 Free PMC article.

6

In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift.

Halliday J, Helmy K, Pattwell SS, Pitter KL, LaPlant Q, Ozawa T, Holland EC. Halliday J, et al. Among authors: ozawa t. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5248-53. doi: 10.1073/pnas.1321014111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706837 Free PMC article.

7

Rethinking glioma treatment strategy.

Ozawa T, Holland EC. Ozawa T, et al. Oncotarget. 2014 Oct 30;5(20):9532-3. doi: 10.18632/oncotarget.2619. Oncotarget. 2014. PMID: 25393981 Free PMC article. No abstract available.

8

Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.

Charles N, Ozawa T, Squatrito M, Bleau AM, Brennan CW, Hambardzumyan D, Holland EC. Charles N, et al. Among authors: ozawa t. Cell Stem Cell. 2010 Feb 5;6(2):141-52. doi: 10.1016/j.stem.2010.01.001. Cell Stem Cell. 2010. PMID: 20144787 Free PMC article.

9

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.

Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC. Bleau AM, et al. Among authors: ozawa t. Cell Stem Cell. 2009 Mar 6;4(3):226-35. doi: 10.1016/j.stem.2009.01.007. Cell Stem Cell. 2009. PMID: 19265662 Free PMC article.

10

Corticosteroids compromise survival in glioblastoma.

Pitter KL, Tamagno I, Alikhanyan K, Hosni-Ahmed A, Pattwell SS, Donnola S, Dai C, Ozawa T, Chang M, Chan TA, Beal K, Bishop AJ, Barker CA, Jones TS, Hentschel B, Gorlia T, Schlegel U, Stupp R, Weller M, Holland EC, Hambardzumyan D. Pitter KL, et al. Among authors: ozawa t. Brain. 2016 May;139(Pt 5):1458-71. doi: 10.1093/brain/aww046. Epub 2016 Mar 28. Brain. 2016. PMID: 27020328 Free PMC article.

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