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Targeting the Jak/Signal Transducer and Activator of Transcription 3 Pathway with Ruxolitinib in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa-Squamous Cell Carcinoma.
Jacków J, Rami A, Hayashi R, Hansen C, Guo Z, DeLorenzo D, Pappalardo A, Alvarez Cespedes D, Kim AL, Perez-Lorenzo R, Owens DM, Christiano AM. Jacków J, et al. Among authors: owens dm. J Invest Dermatol. 2021 Apr;141(4):942-946. doi: 10.1016/j.jid.2020.08.022. Epub 2020 Oct 16. J Invest Dermatol. 2021. PMID: 33069729 Free article. No abstract available.
Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response.
Cohen AO, Woo SH, Zhang J, Cho J, Ruiz ME, Gong J, Du R, Yarygina O, Jafri DZ, Bachelor MA, Finlayson MO, Soni RK, Hayden MS, Owens DM. Cohen AO, et al. Among authors: owens dm. Oncoimmunology. 2022 Nov 2;11(1):2141011. doi: 10.1080/2162402X.2022.2141011. eCollection 2022. Oncoimmunology. 2022. PMID: 36338148 Free PMC article.
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma.
Morgado-Palacin L, Brown JA, Martinez TF, Garcia-Pedrero JM, Forouhar F, Quinn SA, Reglero C, Vaughan J, Heydary YH, Donaldson C, Rodriguez-Perales S, Allonca E, Granda-Diaz R, Fernandez AF, Fraga MF, Kim AL, Santos-Juanes J, Owens DM, Rodrigo JP, Saghatelian A, Ferrando AA. Morgado-Palacin L, et al. Among authors: owens dm. Nat Commun. 2023 Mar 10;14(1):1328. doi: 10.1038/s41467-023-36713-8. Nat Commun. 2023. PMID: 36899004 Free PMC article.
61 results