Wijesekara N - Search Results

1

Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8.

Hardy AB, Wijesekara N, Genkin I, Prentice KJ, Bhattacharjee A, Kong D, Chimienti F, Wheeler MB. Hardy AB, et al. Among authors: wijesekara n. Am J Physiol Endocrinol Metab. 2012 May 15;302(9):E1084-96. doi: 10.1152/ajpendo.00448.2011. Epub 2012 Feb 14. Am J Physiol Endocrinol Metab. 2012. PMID: 22338079 Free PMC article.

2

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB. Wijesekara N, et al. Diabetologia. 2010 Aug;53(8):1656-68. doi: 10.1007/s00125-010-1733-9. Epub 2010 Apr 28. Diabetologia. 2010. PMID: 20424817 Free PMC article.

3

Regulation of glucagon secretion by zinc: lessons from the β cell-specific Znt8 knockout mouse model.

Hardy AB, Serino AS, Wijesekara N, Chimienti F, Wheeler MB. Hardy AB, et al. Among authors: wijesekara n. Diabetes Obes Metab. 2011 Oct;13 Suppl 1:112-7. doi: 10.1111/j.1463-1326.2011.01451.x. Diabetes Obes Metab. 2011. PMID: 21824264 Review.

4

Zinc, a regulator of islet function and glucose homeostasis.

Wijesekara N, Chimienti F, Wheeler MB. Wijesekara N, et al. Diabetes Obes Metab. 2009 Nov;11 Suppl 4:202-14. doi: 10.1111/j.1463-1326.2009.01110.x. Diabetes Obes Metab. 2009. PMID: 19817803 Review.

5

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

Gyulkhandanyan AV, Lu H, Lee SC, Bhattacharjee A, Wijesekara N, Fox JE, MacDonald PE, Chimienti F, Dai FF, Wheeler MB. Gyulkhandanyan AV, et al. Among authors: wijesekara n. J Biol Chem. 2008 Apr 11;283(15):10184-97. doi: 10.1074/jbc.M707005200. Epub 2008 Feb 4. J Biol Chem. 2008. PMID: 18250168 Free article.

6

Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets.

Hardy AB, Fox JE, Giglou PR, Wijesekara N, Bhattacharjee A, Sultan S, Gyulkhandanyan AV, Gaisano HY, MacDonald PE, Wheeler MB. Hardy AB, et al. Among authors: wijesekara n. J Biol Chem. 2009 Oct 30;284(44):30441-52. doi: 10.1074/jbc.M109.040659. Epub 2009 Aug 18. J Biol Chem. 2009. PMID: 19690348 Free PMC article.

7

Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice.

Fu A, Ng AC, Depatie C, Wijesekara N, He Y, Wang GS, Bardeesy N, Scott FW, Touyz RM, Wheeler MB, Screaton RA. Fu A, et al. Among authors: wijesekara n. Cell Metab. 2009 Oct;10(4):285-95. doi: 10.1016/j.cmet.2009.08.008. Cell Metab. 2009. PMID: 19808021 Free article.

8

Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.

Wijesekara N, Krishnamurthy M, Bhattacharjee A, Suhail A, Sweeney G, Wheeler MB. Wijesekara N, et al. J Biol Chem. 2010 Oct 29;285(44):33623-31. doi: 10.1074/jbc.M109.085084. Epub 2010 Aug 13. J Biol Chem. 2010. PMID: 20709750 Free PMC article.

9

Pancreatic β cell-selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis.

Xu J, Wijesekara N, Regeenes R, Rijjal DA, Piro AL, Song Y, Wu A, Bhattacharjee A, Liu Y, Marzban L, Rocheleau JV, Fraser PE, Dai FF, Hu C, Wheeler MB. Xu J, et al. Among authors: wijesekara n. JCI Insight. 2021 May 24;6(10):e143037. doi: 10.1172/jci.insight.143037. JCI Insight. 2021. PMID: 34027899 Free PMC article.

10

The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach.

Lu H, Yang Y, Allister EM, Wijesekara N, Wheeler MB. Lu H, et al. Among authors: wijesekara n. Mol Cell Proteomics. 2008 Aug;7(8):1434-51. doi: 10.1074/mcp.M700478-MCP200. Epub 2008 Apr 30. Mol Cell Proteomics. 2008. PMID: 18448419 Free PMC article.

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