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Page 1
Structural Requirements for CNS Active Opioid Glycopeptides.
Lefever M, Li Y, Anglin B, Muthu D, Giuvelis D, Lowery JJ, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Lefever M, et al. J Med Chem. 2015 Aug 13;58(15):5728-41. doi: 10.1021/acs.jmedchem.5b00014. Epub 2015 Jul 23. J Med Chem. 2015. PMID: 26125201
Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.
Verheijen JC, Richard DJ, Curran K, Kaplan J, Lefever M, Nowak P, Malwitz DJ, Brooijmans N, Toral-Barza L, Zhang WG, Lucas J, Hollander I, Ayral-Kaloustian S, Mansour TS, Yu K, Zask A. Verheijen JC, et al. J Med Chem. 2009 Dec 24;52(24):8010-24. doi: 10.1021/jm9013828. J Med Chem. 2009. PMID: 19894727
Brightfield multiplex immunohistochemistry with multispectral imaging.
Morrison LE, Lefever MR, Behman LJ, Leibold T, Roberts EA, Horchner UB, Bauer DR. Morrison LE, et al. Among authors: lefever mr. Lab Invest. 2020 Aug;100(8):1124-1136. doi: 10.1038/s41374-020-0429-0. Epub 2020 Apr 27. Lab Invest. 2020. PMID: 32341516 Free PMC article.
Fully automated 5-plex fluorescent immunohistochemistry with tyramide signal amplification and same species antibodies.
Zhang W, Hubbard A, Jones T, Racolta A, Bhaumik S, Cummins N, Zhang L, Garsha K, Ventura F, Lefever MR, Lu Z, Hurley JK, Day WA, Pestic-Dragovich L, Morrison LE, Tang L. Zhang W, et al. Among authors: lefever mr. Lab Invest. 2017 Jul;97(7):873-885. doi: 10.1038/labinvest.2017.37. Epub 2017 May 15. Lab Invest. 2017. PMID: 28504684 Free article.