Chen KG - Search Results

1

Molecular pathways: regulation and therapeutic implications of multidrug resistance.

Chen KG, Sikic BI. Chen KG, et al. Clin Cancer Res. 2012 Apr 1;18(7):1863-9. doi: 10.1158/1078-0432.CCR-11-1590. Epub 2012 Feb 16. Clin Cancer Res. 2012. PMID: 22344233 Free PMC article. Review.

2

Preferential expression of a mutant allele of the amplified MDR1 (ABCB1) gene in drug-resistant variants of a human sarcoma.

Chen KG, Lacayo NJ, Durán GE, Wang Y, Bangs CD, Rea S, Kovacs M, Cherry AM, Brown JM, Sikic BI. Chen KG, et al. Genes Chromosomes Cancer. 2002 Aug;34(4):372-83. doi: 10.1002/gcc.10067. Genes Chromosomes Cancer. 2002. PMID: 12112526

3

CCAAT/enhancer-binding protein beta (nuclear factor for interleukin 6) transactivates the human MDR1 gene by interaction with an inverted CCAAT box in human cancer cells.

Chen KG, Sale S, Tan T, Ermoian RP, Sikic BI. Chen KG, et al. Mol Pharmacol. 2004 Apr;65(4):906-16. doi: 10.1124/mol.65.4.906. Mol Pharmacol. 2004. PMID: 15044620

4

Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.

Chen KG, Wang YC, Schaner ME, Francisco B, Durán GE, Juric D, Huff LM, Padilla-Nash H, Ried T, Fojo T, Sikic BI. Chen KG, et al. Cancer Res. 2005 Oct 15;65(20):9388-97. doi: 10.1158/0008-5472.CAN-04-4133. Cancer Res. 2005. PMID: 16230402

5

Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833.

Beketic-Oreskovic L, Durán GE, Chen KG, Dumontet C, Sikic BI. Beketic-Oreskovic L, et al. Among authors: chen kg. J Natl Cancer Inst. 1995 Nov 1;87(21):1593-602. doi: 10.1093/jnci/87.21.1593. J Natl Cancer Inst. 1995. PMID: 7563202

6

Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection.

Chen KG, Jaffrézou JP, Fleming WH, Durán GE, Sikic BI. Chen KG, et al. Cancer Res. 1994 Sep 15;54(18):4980-7. Cancer Res. 1994. PMID: 7915196

7

Volume-activated chloride current is not related to P-glycoprotein overexpression.

Dong Y, Chen KG, Durán GE, Kouyama K, Chao AC, Sikic BI, Gollapudi SV, Gupta S, Gardner P. Dong Y, et al. Among authors: chen kg. Cancer Res. 1994 Oct 1;54(19):5029-32. Cancer Res. 1994. PMID: 7923110

8

Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines.

Wang YC, Juric D, Francisco B, Yu RX, Duran GE, Chen KG, Chen X, Sikic BI. Wang YC, et al. Among authors: chen kg, chen x. Genes Chromosomes Cancer. 2006 Apr;45(4):365-74. doi: 10.1002/gcc.20300. Genes Chromosomes Cancer. 2006. PMID: 16382445

9

Genomic stability at the coding regions of the multidrug transporter gene ABCB1: insights into the development of alternative drug resistance mechanisms in human leukemia cells.

Chen KG, Duran GE, Mogul MJ, Wang YC, Ross KL, Jaffrézou JP, Huff LM, Johnson KR, Fojo T, Lacayo NJ, Sikic BI. Chen KG, et al. Cancer Drug Resist. 2020;3(4):959-979. doi: 10.20517/cdr.2020.51. Epub 2020 Nov 3. Cancer Drug Resist. 2020. PMID: 34541464 Free PMC article.

10

Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance.

Jaffrézou JP, Chen KG, Durán GE, Muller C, Bordier C, Laurent G, Sikic BI, Levade T. Jaffrézou JP, et al. Among authors: chen kg. Biochim Biophys Acta. 1995 Apr 6;1266(1):1-8. doi: 10.1016/0167-4889(94)00219-5. Biochim Biophys Acta. 1995. PMID: 7718613 Free article.

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