Raub TJ - Search Results

1

How well do lipophilicity parameters, MEEKC microemulsion capacity factor, and plasma protein binding predict CNS tissue binding?

Zamek-Gliszczynski MJ, Sprague KE, Espada A, Raub TJ, Morton SM, Manro JR, Molina-Martin M. Zamek-Gliszczynski MJ, et al. Among authors: raub tj. J Pharm Sci. 2012 May;101(5):1932-40. doi: 10.1002/jps.23081. Epub 2012 Feb 17. J Pharm Sci. 2012. PMID: 22344827

2

QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, K_p,uu,brain: Incorporating P-glycoprotein Efflux as a Variable.

Dolgikh E, Watson IA, Desai PV, Sawada GA, Morton S, Jones TM, Raub TJ. Dolgikh E, et al. Among authors: raub tj. J Chem Inf Model. 2016 Nov 28;56(11):2225-2233. doi: 10.1021/acs.jcim.6b00229. Epub 2016 Oct 13. J Chem Inf Model. 2016. PMID: 27684523

3

Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers?

Joshi EM, Need A, Schaus J, Chen Z, Benesh D, Mitch C, Morton S, Raub TJ, Phebus L, Barth V. Joshi EM, et al. Among authors: raub tj. ACS Chem Neurosci. 2014 Dec 17;5(12):1154-63. doi: 10.1021/cn500073j. Epub 2014 Oct 13. ACS Chem Neurosci. 2014. PMID: 25247893 Review.

4

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice.

Nezasa K, Tian X, Zamek-Gliszczynski MJ, Patel NJ, Raub TJ, Brouwer KL. Nezasa K, et al. Among authors: raub tj. Drug Metab Dispos. 2006 Apr;34(4):718-23. doi: 10.1124/dmd.105.007922. Epub 2006 Jan 24. Drug Metab Dispos. 2006. PMID: 16434545

5

A Tribute to Ronald T. Borchardt--Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man.

Schowen KB, Schowen RL, Borchardt SE, Borchardt PM, Artursson P, Audus KL, Augustijns P, Nicolazzo JA, Raub TJ, Schöneich C, Siahaan TJ, Takakura Y, Thakker DR, Wolfe MS. Schowen KB, et al. Among authors: raub tj. J Pharm Sci. 2016 Feb;105(2):370-385. doi: 10.1002/jps.24687. Epub 2016 Jan 29. J Pharm Sci. 2016. PMID: 26453244 Free article. No abstract available.

6

Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.

Tian X, Li J, Zamek-Gliszczynski MJ, Bridges AS, Zhang P, Patel NJ, Raub TJ, Pollack GM, Brouwer KL. Tian X, et al. Among authors: raub tj. Antimicrob Agents Chemother. 2007 Sep;51(9):3230-4. doi: 10.1128/AAC.00082-07. Epub 2007 Jun 18. Antimicrob Agents Chemother. 2007. PMID: 17576841 Free PMC article.

7

The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.

Zamek-Gliszczynski MJ, Nezasa K, Tian X, Kalvass JC, Patel NJ, Raub TJ, Brouwer KL. Zamek-Gliszczynski MJ, et al. Among authors: raub tj. Mol Pharmacol. 2006 Dec;70(6):2127-33. doi: 10.1124/mol.106.026955. Epub 2006 Sep 7. Mol Pharmacol. 2006. PMID: 16959944

8

Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.

Tian X, Zamek-Gliszczynski MJ, Li J, Bridges AS, Nezasa K, Patel NJ, Raub TJ, Brouwer KL. Tian X, et al. Among authors: raub tj. Drug Metab Dispos. 2008 Jan;36(1):61-4. doi: 10.1124/dmd.107.017319. Epub 2007 Oct 3. Drug Metab Dispos. 2008. PMID: 17913796 Free PMC article.

9

Transcellular permeability of chlorpromazine demonstrating the roles of protein binding and membrane partitioning.

Sawada GA, Ho NF, Williams LR, Barsuhn CL, Raub TJ. Sawada GA, et al. Among authors: raub tj. Pharm Res. 1994 May;11(5):665-73. doi: 10.1023/a:1018916027099. Pharm Res. 1994. PMID: 8058634

10

Integration of in silico and in vitro tools for scaffold optimization during drug discovery: predicting P-glycoprotein efflux.

Desai PV, Sawada GA, Watson IA, Raub TJ. Desai PV, et al. Among authors: raub tj. Mol Pharm. 2013 Apr 1;10(4):1249-61. doi: 10.1021/mp300555n. Epub 2013 Mar 1. Mol Pharm. 2013. PMID: 23363443

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