House CM - Search Results

1

Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.

Wong CS, Sceneay J, House CM, Halse HM, Liu MC, George J, Hunnam TC, Parker BS, Haviv I, Ronai Z, Cullinane C, Bowtell DD, Möller A. Wong CS, et al. Among authors: house cm. Cancer Res. 2012 Apr 1;72(7):1694-704. doi: 10.1158/0008-5472.CAN-11-3310. Epub 2012 Feb 21. Cancer Res. 2012. PMID: 22354750

2

Inhibition of Siah ubiquitin ligase function.

Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Möller A, et al. Among authors: house cm. Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13. Oncogene. 2009. PMID: 18850011 Free PMC article.

3

Siah proteins: novel drug targets in the Ras and hypoxia pathways.

House CM, Möller A, Bowtell DD. House CM, et al. Cancer Res. 2009 Dec 1;69(23):8835-8. doi: 10.1158/0008-5472.CAN-09-1676. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920190 Review.

4

IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.

Anglesio MS, George J, Kulbe H, Friedlander M, Rischin D, Lemech C, Power J, Coward J, Cowin PA, House CM, Chakravarty P, Gorringe KL, Campbell IG; Australian Ovarian Cancer Study Group; Okamoto A, Birrer MJ, Huntsman DG, de Fazio A, Kalloger SE, Balkwill F, Gilks CB, Bowtell DD. Anglesio MS, et al. Among authors: house cm. Clin Cancer Res. 2011 Apr 15;17(8):2538-48. doi: 10.1158/1078-0432.CCR-10-3314. Epub 2011 Feb 22. Clin Cancer Res. 2011. PMID: 21343371 Clinical Trial.

5

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.

Chen A, Wong CS, Liu MC, House CM, Sceneay J, Bowtell DD, Thompson EW, Möller A. Chen A, et al. Among authors: house cm. Oncotarget. 2015 Jan 20;6(2):862-73. doi: 10.18632/oncotarget.2696. Oncotarget. 2015. PMID: 25528765 Free PMC article.

6

The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.

Dickins RA, Frew IJ, House CM, O'Bryan MK, Holloway AJ, Haviv I, Traficante N, de Kretser DM, Bowtell DD. Dickins RA, et al. Among authors: house cm. Mol Cell Biol. 2002 Apr;22(7):2294-303. doi: 10.1128/MCB.22.7.2294-2303.2002. Mol Cell Biol. 2002. PMID: 11884614 Free PMC article.

7

Elucidation of the substrate binding site of Siah ubiquitin ligase.

House CM, Hancock NC, Möller A, Cromer BA, Fedorov V, Bowtell DD, Parker MW, Polekhina G. House CM, et al. Structure. 2006 Apr;14(4):695-701. doi: 10.1016/j.str.2005.12.013. Structure. 2006. PMID: 16615911 Free article.

8

Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.

Polekhina G, House CM, Traficante N, Mackay JP, Relaix F, Sassoon DA, Parker MW, Bowtell DD. Polekhina G, et al. Among authors: house cm. Nat Struct Biol. 2002 Jan;9(1):68-75. doi: 10.1038/nsb743. Nat Struct Biol. 2002. PMID: 11742346

9

A binding motif for Siah ubiquitin ligase.

House CM, Frew IJ, Huang HL, Wiche G, Traficante N, Nice E, Catimel B, Bowtell DD. House CM, et al. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3101-6. doi: 10.1073/pnas.0534783100. Epub 2003 Mar 7. Proc Natl Acad Sci U S A. 2003. PMID: 12626763 Free PMC article.

10

The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study.

Millward MJ, House C, Bowtell D, Webster L, Olver IN, Gore M, Copeman M, Lynch K, Yap A, Wang Y, Cohen PS, Zalcberg J. Millward MJ, et al. Br J Cancer. 2006 Oct 9;95(7):829-34. doi: 10.1038/sj.bjc.6603331. Epub 2006 Sep 12. Br J Cancer. 2006. PMID: 16969355 Free PMC article. Clinical Trial.

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