Cole DJ - Search Results

1

Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.

Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig DH, Salem ML, Paulos CM, Cole DJ. Rubinstein MP, et al. Among authors: cole dj. J Am Coll Surg. 2012 Apr;214(4):700-7; discussion 707-8. doi: 10.1016/j.jamcollsurg.2011.12.034. Epub 2012 Feb 22. J Am Coll Surg. 2012. PMID: 22360982 Free PMC article.

2

Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells.

Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE, Cole DJ. Rubinstein MP, et al. Among authors: cole dj. J Immunol. 2002 Nov 1;169(9):4928-35. doi: 10.4049/jimmunol.169.9.4928. J Immunol. 2002. PMID: 12391205

3

Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity.

Rubinstein MP, Kadima AN, Salem ML, Nguyen CL, Gillanders WE, Nishimura MI, Cole DJ. Rubinstein MP, et al. Among authors: cole dj. J Immunol. 2003 Feb 1;170(3):1209-17. doi: 10.4049/jimmunol.170.3.1209. J Immunol. 2003. PMID: 12538678

4

CD8-independent tumor cell recognition is a property of the T cell receptor and not the T cell.

Roszkowski JJ, Yu DC, Rubinstein MP, McKee MD, Cole DJ, Nishimura MI. Roszkowski JJ, et al. Among authors: cole dj. J Immunol. 2003 Mar 1;170(5):2582-9. doi: 10.4049/jimmunol.170.5.2582. J Immunol. 2003. PMID: 12594285

5

Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2).

Nguyen CL, Salem ML, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Nguyen CL, et al. Among authors: cole dj. Vaccine. 2003 Jun 2;21(19-20):2318-28. doi: 10.1016/s0264-410x(03)00096-3. Vaccine. 2003. PMID: 12744862

6

Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine.

Salem ML, Kadima AN, Zhou Y, Nguyen CL, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ, Gillanders WE. Salem ML, et al. Among authors: cole dj. J Immunol. 2004 May 1;172(9):5159-67. doi: 10.4049/jimmunol.172.9.5159. J Immunol. 2004. PMID: 15100252

7

EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy.

Osta WA, Chen Y, Mikhitarian K, Mitas M, Salem M, Hannun YA, Cole DJ, Gillanders WE. Osta WA, et al. Among authors: cole dj. Cancer Res. 2004 Aug 15;64(16):5818-24. doi: 10.1158/0008-5472.CAN-04-0754. Cancer Res. 2004. PMID: 15313925

8

Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity.

Salem ML, Kadima AN, Cole DJ, Gillanders WE. Salem ML, et al. Among authors: cole dj. J Immunother. 2005 May-Jun;28(3):220-8. doi: 10.1097/01.cji.0000156828.75196.0d. J Immunother. 2005. PMID: 15838378

9

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu.

Salem ML, El-Naggar SA, Kadima A, Gillanders WE, Cole DJ. Salem ML, et al. Among authors: cole dj. Vaccine. 2006 Jun 12;24(24):5119-32. doi: 10.1016/j.vaccine.2006.04.010. Epub 2006 May 2. Vaccine. 2006. PMID: 16704888

10

Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.

Salem ML, Gillanders WE, Kadima AN, El-Naggar S, Rubinstein MP, Demcheva M, Vournakis JN, Cole DJ. Salem ML, et al. Among authors: cole dj. J Interferon Cytokine Res. 2006 Sep;26(9):593-608. doi: 10.1089/jir.2006.26.593. J Interferon Cytokine Res. 2006. PMID: 16978064 Review.

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