Brown ML - Search Results

1

Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.

Timofeeva OA, Chasovskikh S, Lonskaya I, Tarasova NI, Khavrutskii L, Tarasov SG, Zhang X, Korostyshevskiy VR, Cheema A, Zhang L, Dakshanamurthy S, Brown ML, Dritschilo A. Timofeeva OA, et al. Among authors: brown ml. J Biol Chem. 2012 Apr 20;287(17):14192-200. doi: 10.1074/jbc.M111.323899. Epub 2012 Feb 29. J Biol Chem. 2012. PMID: 22378781 Free PMC article.

2

STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain.

Timofeeva OA, Tarasova NI, Zhang X, Chasovskikh S, Cheema AK, Wang H, Brown ML, Dritschilo A. Timofeeva OA, et al. Among authors: brown ml. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1267-72. doi: 10.1073/pnas.1211805110. Epub 2013 Jan 3. Proc Natl Acad Sci U S A. 2013. PMID: 23288901 Free PMC article.

3

Enhanced expression of SOS1 is detected in prostate cancer epithelial cells from African-American men.

Timofeeva OA, Zhang X, Ressom HW, Varghese RS, Kallakury BV, Wang K, Ji Y, Cheema A, Jung M, Brown ML, Rhim JS, Dritschilo A. Timofeeva OA, et al. Among authors: brown ml. Int J Oncol. 2009 Oct;35(4):751-60. Int J Oncol. 2009. PMID: 19724911 Free PMC article.

4

In-silico fragment-based identification of novel angiogenesis inhibitors.

Dakshanamurthy S, Kim M, Brown ML, Byers SW. Dakshanamurthy S, et al. Among authors: brown ml. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4551-6. doi: 10.1016/j.bmcl.2007.05.104. Epub 2007 Jun 15. Bioorg Med Chem Lett. 2007. PMID: 17591441

5

Histone deacetylase cytoplasmic trapping by a novel fluorescent HDAC inhibitor.

Kong Y, Jung M, Wang K, Grindrod S, Velena A, Lee SA, Dakshanamurthy S, Yang Y, Miessau M, Zheng C, Dritschilo A, Brown ML. Kong Y, et al. Among authors: brown ml. Mol Cancer Ther. 2011 Sep;10(9):1591-9. doi: 10.1158/1535-7163.MCT-10-0779. Epub 2011 Jun 22. Mol Cancer Ther. 2011. PMID: 21697394 Free PMC article.

6

Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells.

Yenugonda VM, Deb TB, Grindrod SC, Dakshanamurthy S, Yang Y, Paige M, Brown ML. Yenugonda VM, et al. Among authors: brown ml. Bioorg Med Chem. 2011 Apr 15;19(8):2714-25. doi: 10.1016/j.bmc.2011.02.052. Epub 2011 Mar 4. Bioorg Med Chem. 2011. PMID: 21440449

7

Predicting new indications for approved drugs using a proteochemometric method.

Dakshanamurthy S, Issa NT, Assefnia S, Seshasayee A, Peters OJ, Madhavan S, Uren A, Brown ML, Byers SW. Dakshanamurthy S, et al. Among authors: brown ml. J Med Chem. 2012 Aug 9;55(15):6832-48. doi: 10.1021/jm300576q. Epub 2012 Jul 25. J Med Chem. 2012. PMID: 22780961 Free PMC article.

8

Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers.

De Oliveira EO, Graf KM, Patel MK, Baheti A, Kong HS, MacArthur LH, Dakshanamurthy S, Wang K, Brown ML, Paige M. De Oliveira EO, et al. Among authors: brown ml. Bioorg Med Chem. 2011 Jul 15;19(14):4322-9. doi: 10.1016/j.bmc.2011.05.043. Epub 2011 May 30. Bioorg Med Chem. 2011. PMID: 21683602 Free PMC article.

9

Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent.

Walls TH, Grindrod SC, Beraud D, Zhang L, Baheti AR, Dakshanamurthy S, Patel MK, Brown ML, MacArthur LH. Walls TH, et al. Among authors: brown ml. Bioorg Med Chem. 2012 Sep 1;20(17):5269-76. doi: 10.1016/j.bmc.2012.06.042. Epub 2012 Jul 3. Bioorg Med Chem. 2012. PMID: 22863530 Free PMC article.

10

Preclinical studies of YK-4-272, an inhibitor of class II histone deacetylases by disruption of nucleocytoplasmic shuttling.

Kong HS, Tian S, Kong Y, Du G, Zhang L, Jung M, Dritschilo A, Brown ML. Kong HS, et al. Among authors: brown ml. Pharm Res. 2012 Dec;29(12):3373-83. doi: 10.1007/s11095-012-0832-3. Epub 2012 Jul 27. Pharm Res. 2012. PMID: 22836184 Free PMC article.

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