Wu D - Search Results

1

Synthesis, structure-activity relationship, and pharmacophore modeling studies of pyrazole-3-carbohydrazone derivatives as dipeptidyl peptidase IV inhibitors.

Wu D, Jin F, Lu W, Zhu J, Li C, Wang W, Tang Y, Jiang H, Huang J, Liu G, Li J. Wu D, et al. Chem Biol Drug Des. 2012 Jun;79(6):897-906. doi: 10.1111/j.1747-0285.2012.01365.x. Epub 2012 Mar 21. Chem Biol Drug Des. 2012. PMID: 22381062

2

Synthesis of highly functionalized chiral 3,3'-disubstituted oxindoles via an organocatalytic enantioselective Michael addition of nitroalkanes to indolylidenecyanoacetates.

Liu L, Wu D, Zheng S, Li T, Li X, Wang S, Li J, Li H, Wang W. Liu L, et al. Among authors: wu d. Org Lett. 2012 Jan 6;14(1):134-7. doi: 10.1021/ol202931e. Epub 2011 Dec 12. Org Lett. 2012. PMID: 22149210

3

Organocatalytic enantioselective conjugate addition of ketones to isatylidine malononitriles.

Liu L, Wu D, Li X, Wang S, Li H, Li J, Wang W. Liu L, et al. Among authors: wu d. Chem Commun (Camb). 2012 Feb 4;48(11):1692-4. doi: 10.1039/c2cc17067a. Epub 2011 Dec 21. Chem Commun (Camb). 2012. PMID: 22190075

4

A strategy enabling enantioselective direct conjugate addition of inert aryl methane nucleophiles to enals with a chiral amine catalyst under mild conditions.

Li T, Zhu J, Wu D, Li X, Wang S, Li H, Li J, Wang W. Li T, et al. Among authors: wu d. Chemistry. 2013 Jul 8;19(28):9147-50. doi: 10.1002/chem.201300304. Epub 2013 May 24. Chemistry. 2013. PMID: 23712495 No abstract available.

5

2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors.

Lang L, Dong N, Wu D, Yao X, Lu W, Zhang C, Ouyang P, Zhu J, Tang Y, Wang W, Li J, Huang J. Lang L, et al. Among authors: wu d. J Enzyme Inhib Med Chem. 2016;31(sup4):98-105. doi: 10.1080/14756366.2016.1220376. Epub 2016 Sep 2. J Enzyme Inhib Med Chem. 2016. PMID: 27590167 Free article.

6

Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.

Qiu X, Huang Y, Wu D, Mao F, Zhu J, Yan W, Luo HB, Li J. Qiu X, et al. Among authors: wu d. Bioorg Med Chem. 2018 Jan 1;26(1):119-133. doi: 10.1016/j.bmc.2017.11.022. Epub 2017 Nov 14. Bioorg Med Chem. 2018. PMID: 29174506

7

Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy.

Cheng Z, Wang Y, Zhang Y, Zhang C, Wang M, Wang W, He J, Wang Y, Zhang H, Zhang Q, Ding C, Wu D, Yang L, Liu M, Lu W. Cheng Z, et al. Among authors: wu d. J Med Chem. 2023 May 11;66(9):6218-6238. doi: 10.1021/acs.jmedchem.2c02058. Epub 2023 Mar 7. J Med Chem. 2023. PMID: 36880691

8

Subtle Structural Modifications Spanning from EP4 Antagonism to EP2/EP4 Dual Antagonism: A Novel Class of Thienocyclic-Based Derivatives.

Cheng Z, Zhang Y, Du L, Wang W, Chai X, He M, Zhang H, Wu D, Lu J, Zhang S, Feng B, Yang L, Liu M, Lu W. Cheng Z, et al. Among authors: wu d. J Med Chem. 2025 Jan 6. doi: 10.1021/acs.jmedchem.4c02241. Online ahead of print. J Med Chem. 2025. PMID: 39757828

9

Discovery of Novel Phosphodiesterase-2A Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay.

Zhang C, Feng LJ, Huang Y, Wu D, Li Z, Zhou Q, Wu Y, Luo HB. Zhang C, et al. Among authors: wu y, wu d. J Chem Inf Model. 2017 Feb 27;57(2):355-364. doi: 10.1021/acs.jcim.6b00551. Epub 2017 Jan 18. J Chem Inf Model. 2017. PMID: 28055196

10

Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors.

Zheng X, Jiang Z, Li X, Zhang C, Li Z, Wu Y, Wang X, Zhang C, Luo HB, Xu J, Wu D. Zheng X, et al. Among authors: wu y, wu d. Bioorg Med Chem. 2018 Dec 1;26(22):5934-5943. doi: 10.1016/j.bmc.2018.10.044. Epub 2018 Nov 3. Bioorg Med Chem. 2018. PMID: 30429100

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