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Re-circulation of lymphocytes mediated by sphingosine-1-phosphate receptor-1 contributes to resistance against experimental infection with the protozoan parasite Trypanosoma cruzi.
Dominguez MR, Ersching J, Lemos R, Machado AV, Bruna-Romero O, Rodrigues MM, de Vasconcelos JR. Dominguez MR, et al. Among authors: machado av. Vaccine. 2012 Apr 16;30(18):2882-91. doi: 10.1016/j.vaccine.2012.02.037. Epub 2012 Feb 28. Vaccine. 2012. PMID: 22381075 Free article.
Strain-specific protective immunity following vaccination against experimental Trypanosoma cruzi infection.
Haolla FA, Claser C, de Alencar BC, Tzelepis F, de Vasconcelos JR, de Oliveira G, Silvério JC, Machado AV, Lannes-Vieira J, Bruna-Romero O, Gazzinelli RT, dos Santos RR, Soares MB, Rodrigues MM. Haolla FA, et al. Among authors: machado av. Vaccine. 2009 Sep 18;27(41):5644-53. doi: 10.1016/j.vaccine.2009.07.013. Epub 2009 Jul 25. Vaccine. 2009. PMID: 19635607 Free article.
Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.
de Alencar BC, Persechini PM, Haolla FA, de Oliveira G, Silverio JC, Lannes-Vieira J, Machado AV, Gazzinelli RT, Bruna-Romero O, Rodrigues MM. de Alencar BC, et al. Among authors: machado av. Infect Immun. 2009 Oct;77(10):4383-95. doi: 10.1128/IAI.01459-08. Epub 2009 Aug 3. Infect Immun. 2009. PMID: 19651871 Free PMC article.
Heterologous plasmid DNA prime-recombinant human adenovirus 5 boost vaccination generates a stable pool of protective long-lived CD8(+) T effector memory cells specific for a human parasite, Trypanosoma cruzi.
Rigato PO, de Alencar BC, de Vasconcelos JR, Dominguez MR, Araújo AF, Machado AV, Gazzinelli RT, Bruna-Romero O, Rodrigues MM. Rigato PO, et al. Among authors: machado av. Infect Immun. 2011 May;79(5):2120-30. doi: 10.1128/IAI.01190-10. Epub 2011 Feb 28. Infect Immun. 2011. PMID: 21357719 Free PMC article.
Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: reversal by adenoviral vaccine.
Vasconcelos JR, Bruña-Romero O, Araújo AF, Dominguez MR, Ersching J, de Alencar BC, Machado AV, Gazzinelli RT, Bortoluci KR, Amarante-Mendes GP, Lopes MF, Rodrigues MM. Vasconcelos JR, et al. Among authors: machado av. PLoS Pathog. 2012;8(5):e1002699. doi: 10.1371/journal.ppat.1002699. Epub 2012 May 17. PLoS Pathog. 2012. PMID: 22615561 Free PMC article.
Adenovirus vector-induced CD8⁺ T effector memory cell differentiation and recirculation, but not proliferation, are important for protective immunity against experimental Trypanosoma cruzi Infection.
Vasconcelos JR, Dominguez MR, Neves RL, Ersching J, Araújo A, Santos LI, Virgilio FS, Machado AV, Bruna-Romero O, Gazzinelli RT, Rodrigues MM. Vasconcelos JR, et al. Among authors: machado av. Hum Gene Ther. 2014 Apr;25(4):350-63. doi: 10.1089/hum.2013.218. Epub 2014 Mar 31. Hum Gene Ther. 2014. PMID: 24568548 Free PMC article.
The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi.
Ersching J, Vasconcelos JR, Ferreira CP, Caetano BC, Machado AV, Bruna-Romero O, Baron MA, Ferreira LR, Cunha-Neto E, Rock KL, Gazzinelli RT, Rodrigues MM. Ersching J, et al. Among authors: machado av. PLoS Pathog. 2016 Apr 29;12(4):e1005593. doi: 10.1371/journal.ppat.1005593. eCollection 2016 Apr. PLoS Pathog. 2016. PMID: 27128676 Free PMC article.
65 results