Zhou Q - Search Results

1

Screening candidate anticancer drugs for brain tumor chemotherapy: pharmacokinetic-driven approach for a series of (E)-N-(substituted aryl)-3-(substituted phenyl)propenamide analogues.

Lv H, Wang F, Reddy MV, Zhou Q, Zhang X, Reddy EP, Gallo JM. Lv H, et al. Among authors: zhou q. Invest New Drugs. 2012 Dec;30(6):2263-73. doi: 10.1007/s10637-012-9806-x. Epub 2012 Mar 1. Invest New Drugs. 2012. PMID: 22383114 Free PMC article.

2

The pharmacokinetic/pharmacodynamic pipeline: translating anticancer drug pharmacology to the clinic.

Zhou Q, Gallo JM. Zhou Q, et al. AAPS J. 2011 Mar;13(1):111-20. doi: 10.1208/s12248-011-9253-1. Epub 2011 Jan 19. AAPS J. 2011. PMID: 21246315 Free PMC article. Review.

3

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models.

Zhang X, Lv H, Zhou Q, Elkholi R, Chipuk JE, Reddy MV, Reddy EP, Gallo JM. Zhang X, et al. Among authors: zhou q. Mol Cancer Ther. 2014 May;13(5):1105-16. doi: 10.1158/1535-7163.MCT-13-0847. Epub 2014 Feb 25. Mol Cancer Ther. 2014. PMID: 24568969 Free PMC article.

4

Multiscale design of cell-type-specific pharmacokinetic/pharmacodynamic models for personalized medicine: application to temozolomide in brain tumors.

Ballesta A, Zhou Q, Zhang X, Lv H, Gallo JM. Ballesta A, et al. Among authors: zhou q. CPT Pharmacometrics Syst Pharmacol. 2014 Apr 30;3(4):e112. doi: 10.1038/psp.2014.9. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 24785551 Free PMC article.

5

Demonstration of the equivalent pharmacokinetic/pharmacodynamic dosing strategy in a multiple-dose study of gefitinib.

Wang S, Zhou Q, Gallo JM. Wang S, et al. Among authors: zhou q. Mol Cancer Ther. 2009 Jun;8(6):1438-47. doi: 10.1158/1535-7163.MCT-09-0089. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509243 Free PMC article.

6

Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for brain tumor chemotherapy.

Nuthalapati S, Zhou Q, Guo P, Lv H, Cosenza S, Reddy MV, Reddy EP, Gallo JM. Nuthalapati S, et al. Among authors: zhou q. Pharm Res. 2012 Sep;29(9):2499-511. doi: 10.1007/s11095-012-0780-y. Epub 2012 Jun 8. Pharm Res. 2012. PMID: 22678771

7

Activation of alternate prosurvival pathways accounts for acquired sunitinib resistance in U87MG glioma xenografts.

Zhou Q, Lv H, Mazloom AR, Xu H, Ma'ayan A, Gallo JM. Zhou Q, et al. J Pharmacol Exp Ther. 2012 Nov;343(2):509-19. doi: 10.1124/jpet.112.196097. Epub 2012 Aug 6. J Pharmacol Exp Ther. 2012. PMID: 22869928 Free PMC article.

8

In vivo microdialysis for PK and PD studies of anticancer drugs.

Zhou Q, Gallo JM. Zhou Q, et al. AAPS J. 2005 Oct 24;7(3):E659-67. doi: 10.1208/aapsj070366. AAPS J. 2005. PMID: 16353942 Free PMC article. Review.

9

Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.

Zhou Q, Guo P, Kruh GD, Vicini P, Wang X, Gallo JM. Zhou Q, et al. Clin Cancer Res. 2007 Jul 15;13(14):4271-9. doi: 10.1158/1078-0432.CCR-07-0658. Clin Cancer Res. 2007. PMID: 17634557

10

Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing regimens in EGFR wild-type and mutant tumor models.

Wang S, Guo P, Wang X, Zhou Q, Gallo JM. Wang S, et al. Among authors: zhou q. Mol Cancer Ther. 2008 Feb;7(2):407-17. doi: 10.1158/1535-7163.MCT-07-2070. Mol Cancer Ther. 2008. PMID: 18281523

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