Santhosh Kumar T - Search Results

1

Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues.

Van Poecke S, Barrett MO, Santhosh Kumar T, Sinnaeve D, Martins JC, Jacobson KA, Kendall Harden T, Van Calenbergh S. Van Poecke S, et al. Among authors: santhosh kumar t. Bioorg Med Chem. 2012 Apr 1;20(7):2304-15. doi: 10.1016/j.bmc.2012.02.012. Epub 2012 Feb 15. Bioorg Med Chem. 2012. PMID: 22386981 Free PMC article.

2

Virtual screening leads to the discovery of novel non-nucleotide P2Y₁ receptor antagonists.

Costanzi S, Santhosh Kumar T, Balasubramanian R, Kendall Harden T, Jacobson KA. Costanzi S, et al. Among authors: santhosh kumar t. Bioorg Med Chem. 2012 Sep 1;20(17):5254-61. doi: 10.1016/j.bmc.2012.06.044. Epub 2012 Jul 3. Bioorg Med Chem. 2012. PMID: 22831801 Free PMC article.

3

Discovery of 3-(benzofuran-2-ylmethyl)-1H-indole derivatives as potential autophagy inducers in cervical cancer cells.

Siddiqui SK, SahayaSheela VJ, Kolluru S, Pandian GN, Santhoshkumar TR, Dan VM, Ramana CV. Siddiqui SK, et al. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127431. doi: 10.1016/j.bmcl.2020.127431. Epub 2020 Jul 23. Bioorg Med Chem Lett. 2020. PMID: 32769048

4

Streptomyces sp metabolite(s) promotes Bax mediated intrinsic apoptosis and autophagy involving inhibition of mTOR pathway in cervical cancer cell lines.

Dan VM, Muralikrishnan B, Sanawar R, J S V, Burkul BB, Srinivas KP, Lekshmi A, Pradeep NS, Dastager SG, Santhakumari B, Santhoshkumar TR, Kumar RA, Pillai MR. Dan VM, et al. Sci Rep. 2018 Feb 12;8(1):2810. doi: 10.1038/s41598-018-21249-5. Sci Rep. 2018. PMID: 29434241 Free PMC article.

5

Molecular Networking and Whole-Genome Analysis Aid Discovery of an Angucycline That Inactivates mTORC1/C2 and Induces Programmed Cell Death.

Dan VM, J S V, C J S, Sanawar R, Lekshmi A, Kumar RA, Santhosh Kumar TR, Marelli UK, Dastager SG, Pillai MR. Dan VM, et al. Among authors: santhosh kumar tr. ACS Chem Biol. 2020 Mar 20;15(3):780-788. doi: 10.1021/acschembio.0c00026. Epub 2020 Feb 25. ACS Chem Biol. 2020. PMID: 32058690

6

DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by up-regulating p38 MAP kinase.

Srinivas KP, Viji R, Dan VM, Sajitha IS, Prakash R, Rahul PV, Santhoshkumar TR, Lakshmi S, Pillai MR. Srinivas KP, et al. Oncotarget. 2016 Apr 26;7(17):24154-71. doi: 10.18632/oncotarget.8131. Oncotarget. 2016. PMID: 26992219 Free PMC article.

7

A reporter cell line for real-time imaging of autophagy and apoptosis.

Lupitha SS, Chandrasekhar L, Varadarajan SN, Jayaprasad AG, Chandrasekharan A, Patil SN, Mini M, Pillai PR, Santhoshkumar TR. Lupitha SS, et al. Toxicol Lett. 2020 Jun 15;326:23-30. doi: 10.1016/j.toxlet.2020.02.011. Epub 2020 Feb 25. Toxicol Lett. 2020. PMID: 32109534

8

Multiple drug resistant, tumorigenic stem-like cells in oral cancer.

Richard V, Sebastian P, Nair MG, Nair SN, Malieckal TT, Santhosh Kumar TR, Pillai MR. Richard V, et al. Among authors: santhosh kumar tr. Cancer Lett. 2013 Sep 28;338(2):300-16. doi: 10.1016/j.canlet.2013.06.011. Epub 2013 Jun 18. Cancer Lett. 2013. PMID: 23791883

9

A high-throughput image-based screen for the identification of Bax/Bak-independent caspase activators against drug-resistant cancer cells.

Seervi M, Sobhan PK, Mathew KA, Joseph J, Pillai PR, Santhoshkumar TR. Seervi M, et al. Apoptosis. 2014 Jan;19(1):269-84. doi: 10.1007/s10495-013-0921-8. Apoptosis. 2014. PMID: 24220853

10

ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine.

Seervi M, Rani A, Sharma AK, Santhosh Kumar TR. Seervi M, et al. Among authors: santhosh kumar tr. Biomed Pharmacother. 2018 Oct;106:200-209. doi: 10.1016/j.biopha.2018.06.123. Epub 2018 Jun 28. Biomed Pharmacother. 2018. PMID: 29960166

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