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Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Jayathilaka N, Han A, Gaffney KJ, Dey R, Jarusiewicz JA, Noridomi K, Philips MA, Lei X, He J, Ye J, Gao T, Petasis NA, Chen L. Jayathilaka N, et al. Among authors: gaffney kj. Nucleic Acids Res. 2012 Jul;40(12):5378-88. doi: 10.1093/nar/gks189. Epub 2012 Mar 6. Nucleic Acids Res. 2012. PMID: 22396528 Free PMC article.
Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors.
Thomas S, Sharma N, Golden EB, Cho H, Agarwal P, Gaffney KJ, Petasis NA, Chen TC, Hofman FM, Louie SG, Schönthal AH. Thomas S, et al. Among authors: gaffney kj. Cancer Lett. 2012 Dec 1;325(1):63-71. doi: 10.1016/j.canlet.2012.05.030. Epub 2012 Jun 1. Cancer Lett. 2012. PMID: 22664238
Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature.
Virrey JJ, Liu Z, Cho HY, Kardosh A, Golden EB, Louie SG, Gaffney KJ, Petasis NA, Schönthal AH, Chen TC, Hofman FM. Virrey JJ, et al. Among authors: gaffney kj. Mol Cancer Ther. 2010 Mar;9(3):631-41. doi: 10.1158/1535-7163.MCT-09-0652. Epub 2010 Mar 2. Mol Cancer Ther. 2010. PMID: 20197398
109 results