Langen R - Search Results

1

Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation.

Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR. Meier F, et al. Among authors: langen r. J Am Chem Soc. 2012 Mar 28;134(12):5468-71. doi: 10.1021/ja300094r. Epub 2012 Mar 14. J Am Chem Soc. 2012. PMID: 22404520 Free PMC article.

2

Structural organization of alpha-synuclein fibrils studied by site-directed spin labeling.

Der-Sarkissian A, Jao CC, Chen J, Langen R. Der-Sarkissian A, et al. Among authors: langen r. J Biol Chem. 2003 Sep 26;278(39):37530-5. doi: 10.1074/jbc.M305266200. Epub 2003 Jun 18. J Biol Chem. 2003. PMID: 12815044 Free article.

3

Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling.

Jao CC, Der-Sarkissian A, Chen J, Langen R. Jao CC, et al. Among authors: langen r. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8331-6. doi: 10.1073/pnas.0400553101. Epub 2004 May 20. Proc Natl Acad Sci U S A. 2004. PMID: 15155902 Free PMC article.

4

Investigation of alpha-synuclein fibril structure by site-directed spin labeling.

Chen M, Margittai M, Chen J, Langen R. Chen M, et al. Among authors: langen r. J Biol Chem. 2007 Aug 24;282(34):24970-9. doi: 10.1074/jbc.M700368200. Epub 2007 Jun 15. J Biol Chem. 2007. PMID: 17573347 Free article.

5

Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement.

Jao CC, Hegde BG, Chen J, Haworth IS, Langen R. Jao CC, et al. Among authors: langen r. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19666-71. doi: 10.1073/pnas.0807826105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066219 Free PMC article.

6

A combinatorial NMR and EPR approach for evaluating the structural ensemble of partially folded proteins.

Rao JN, Jao CC, Hegde BG, Langen R, Ulmer TS. Rao JN, et al. Among authors: langen r. J Am Chem Soc. 2010 Jun 30;132(25):8657-68. doi: 10.1021/ja100646t. J Am Chem Soc. 2010. PMID: 20524659 Free PMC article.

7

Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins.

Varkey J, Isas JM, Mizuno N, Jensen MB, Bhatia VK, Jao CC, Petrlova J, Voss JC, Stamou DG, Steven AC, Langen R. Varkey J, et al. Among authors: langen r. J Biol Chem. 2010 Oct 15;285(42):32486-93. doi: 10.1074/jbc.M110.139576. Epub 2010 Aug 6. J Biol Chem. 2010. PMID: 20693280 Free PMC article.

8

Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation.

Mizuno N, Varkey J, Kegulian NC, Hegde BG, Cheng N, Langen R, Steven AC. Mizuno N, et al. Among authors: langen r. J Biol Chem. 2012 Aug 24;287(35):29301-11. doi: 10.1074/jbc.M112.365817. Epub 2012 Jul 5. J Biol Chem. 2012. PMID: 22767608 Free PMC article.

9

Rational design of potent domain antibody inhibitors of amyloid fibril assembly.

Ladiwala AR, Bhattacharya M, Perchiacca JM, Cao P, Raleigh DP, Abedini A, Schmidt AM, Varkey J, Langen R, Tessier PM. Ladiwala AR, et al. Among authors: langen r. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19965-70. doi: 10.1073/pnas.1208797109. Epub 2012 Nov 15. Proc Natl Acad Sci U S A. 2012. PMID: 23161913 Free PMC article.

10

α-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles.

Varkey J, Mizuno N, Hegde BG, Cheng N, Steven AC, Langen R. Varkey J, et al. Among authors: langen r. J Biol Chem. 2013 Jun 14;288(24):17620-30. doi: 10.1074/jbc.M113.476697. Epub 2013 Apr 22. J Biol Chem. 2013. PMID: 23609437 Free PMC article.

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