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HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase.
Lecoeur H, Borgne-Sanchez A, Chaloin O, El-Khoury R, Brabant M, Langonné A, Porceddu M, Brière JJ, Buron N, Rebouillat D, Péchoux C, Deniaud A, Brenner C, Briand JP, Muller S, Rustin P, Jacotot E. Lecoeur H, et al. Among authors: rustin p. Cell Death Dis. 2012 Mar 15;3(3):e282. doi: 10.1038/cddis.2012.21. Cell Death Dis. 2012. PMID: 22419111 Free PMC article.
Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.
Borgne-Sanchez A, Dupont S, Langonné A, Baux L, Lecoeur H, Chauvier D, Lassalle M, Déas O, Brière JJ, Brabant M, Roux P, Péchoux C, Briand JP, Hoebeke J, Deniaud A, Brenner C, Rustin P, Edelman L, Rebouillat D, Jacotot E. Borgne-Sanchez A, et al. Among authors: rustin p. Cell Death Differ. 2007 Mar;14(3):422-35. doi: 10.1038/sj.cdd.4402018. Epub 2006 Aug 4. Cell Death Differ. 2007. PMID: 16888644
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.
Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J, Rustin P, Métivier D, Lenoir C, Geuskens M, Vieira HL, Loeffler M, Belzacq AS, Briand JP, Zamzami N, Edelman L, Xie ZH, Reed JC, Roques BP, Kroemer G. Jacotot E, et al. Among authors: rustin p. J Exp Med. 2001 Feb 19;193(4):509-19. doi: 10.1084/jem.193.4.509. J Exp Med. 2001. PMID: 11181702 Free PMC article.
Mitochondrial cytochrome c oxidase deficiency.
Rak M, Bénit P, Chrétien D, Bouchereau J, Schiff M, El-Khoury R, Tzagoloff A, Rustin P. Rak M, et al. Among authors: rustin p. Clin Sci (Lond). 2016 Mar;130(6):393-407. doi: 10.1042/CS20150707. Clin Sci (Lond). 2016. PMID: 26846578 Free PMC article. Review.
Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor.
Chauvier D, Renolleau S, Holifanjaniaina S, Ankri S, Bezault M, Schwendimann L, Rousset C, Casimir R, Hoebeke J, Smirnova M, Debret G, Trichet AP, Carlsson Y, Wang X, Bernard E, Hébert M, Rauzier JM, Matecki S, Lacampagne A, Rustin P, Mariani J, Hagberg H, Gressens P, Charriaut-Marlangue C, Jacotot E. Chauvier D, et al. Among authors: rustin p. Cell Death Dis. 2011 Sep 1;2(9):e203. doi: 10.1038/cddis.2011.87. Cell Death Dis. 2011. PMID: 21881605 Free PMC article.
Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction.
El-Khoury R, Dufour E, Rak M, Ramanantsoa N, Grandchamp N, Csaba Z, Duvillié B, Bénit P, Gallego J, Gressens P, Sarkis C, Jacobs HT, Rustin P. El-Khoury R, et al. Among authors: rustin p. PLoS Genet. 2013;9(1):e1003182. doi: 10.1371/journal.pgen.1003182. Epub 2013 Jan 3. PLoS Genet. 2013. PMID: 23300486 Free PMC article.
322 results