Moschel RC - Search Results

1

Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.

Dolan ME, Stine L, Mitchell RB, Moschel RC, Pegg AE. Dolan ME, et al. Among authors: moschel rc. Cancer Commun. 1990;2(11):371-7. doi: 10.3727/095535490820873985. Cancer Commun. 1990. PMID: 2242301

2

Enhancement of platinum-induced cytotoxicity by O6-benzylguanine.

Fishel ML, Delaney SM, Friesen LD, Hansen RJ, Zuhowski EG, Moschel RC, Egorin MJ, Dolan ME. Fishel ML, et al. Among authors: moschel rc. Mol Cancer Ther. 2003 Jul;2(7):633-40. Mol Cancer Ther. 2003. PMID: 12883036

3

Effects of inhibition of O6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea.

Lijinsky W, Pegg AE, Anver MR, Moschel RC. Lijinsky W, et al. Among authors: moschel rc. Jpn J Cancer Res. 1994 Mar;85(3):226-30. doi: 10.1111/j.1349-7006.1994.tb02086.x. Jpn J Cancer Res. 1994. PMID: 8188519 Free PMC article.

4

Treatment of subcutaneous and intracranial brain tumor xenografts with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.

Felker GM, Friedman HS, Dolan ME, Moschel RC, Schold C. Felker GM, et al. Among authors: moschel rc. Cancer Chemother Pharmacol. 1993;32(6):471-6. doi: 10.1007/BF00685892. Cancer Chemother Pharmacol. 1993. PMID: 8258196

5

Substituted O6-benzylguanine derivatives and their inactivation of human O6-alkylguanine-DNA alkyltransferase.

Chae MY, McDougall MG, Dolan ME, Swenn K, Pegg AE, Moschel RC. Chae MY, et al. Among authors: moschel rc. J Med Chem. 1994 Feb 4;37(3):342-7. doi: 10.1021/jm00029a005. J Med Chem. 1994. PMID: 8308861

6

Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).

Dolan ME, Pegg AE, Moschel RC, Grindey GB. Dolan ME, et al. Among authors: moschel rc. Biochem Pharmacol. 1993 Jul 20;46(2):285-90. doi: 10.1016/0006-2952(93)90416-t. Biochem Pharmacol. 1993. PMID: 8347150

7

Effect of O6-benzylguanine on the response to 1,3-bis(2-chloroethyl)-1-nitrosourea in the Dunning R3327G model of prostatic cancer.

Dolan ME, Pegg AE, Biser ND, Moschel RC, English HF. Dolan ME, et al. Among authors: moschel rc. Cancer Chemother Pharmacol. 1993;32(3):221-5. doi: 10.1007/BF00685839. Cancer Chemother Pharmacol. 1993. PMID: 8500228

8

Pharmacokinetics and metabolism in rats of 2,4-diamino-6-benzyloxy-5- nitrosopyrimidine, an inactivator of O6-alkylguanine-DNA alkyltransferase.

Roy SK, Moschel RC, Dolan ME. Roy SK, et al. Among authors: moschel rc. Drug Metab Dispos. 1996 Nov;24(11):1205-11. Drug Metab Dispos. 1996. PMID: 8937854

9

Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea.

Kurpad SN, Dolan ME, McLendon RE, Archer GE, Moschel RC, Pegg AE, Bigner DD, Friedman HS. Kurpad SN, et al. Among authors: moschel rc. Cancer Chemother Pharmacol. 1997;39(4):307-16. doi: 10.1007/s002800050577. Cancer Chemother Pharmacol. 1997. PMID: 9025771

10

O6-alkylguanine-DNA alkyltransferase inactivation by ester prodrugs of O6-benzylguanine derivatives and their rate of hydrolysis by cellular esterases.

Dolan ME, Roy SK, Garbiras BJ, Helft P, Paras P, Chae MY, Moschel RC, Pegg AE. Dolan ME, et al. Among authors: moschel rc. Biochem Pharmacol. 1998 May 15;55(10):1701-9. doi: 10.1016/s0006-2952(98)00047-1. Biochem Pharmacol. 1998. PMID: 9634007

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