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Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylation.
Ginter T, Bier C, Knauer SK, Sughra K, Hildebrand D, Münz T, Liebe T, Heller R, Henke A, Stauber RH, Reichardt W, Schmid JA, Kubatzky KF, Heinzel T, Krämer OH. Ginter T, et al. Among authors: kramer oh. Cell Signal. 2012 Jul;24(7):1453-60. doi: 10.1016/j.cellsig.2012.02.018. Epub 2012 Mar 7. Cell Signal. 2012. PMID: 22425562
Histone deacetylase as a therapeutic target.
Krämer OH, Göttlicher M, Heinzel T. Krämer OH, et al. Trends Endocrinol Metab. 2001 Sep;12(7):294-300. doi: 10.1016/s1043-2760(01)00438-6. Trends Endocrinol Metab. 2001. PMID: 11504668 Review.
Acetylation of Stat1 modulates NF-kappaB activity.
Krämer OH, Baus D, Knauer SK, Stein S, Jäger E, Stauber RH, Grez M, Pfitzner E, Heinzel T. Krämer OH, et al. Genes Dev. 2006 Feb 15;20(4):473-85. doi: 10.1101/gad.364306. Genes Dev. 2006. PMID: 16481475 Free PMC article.
Nuclear export is essential for the tumor-promoting activity of survivin.
Knauer SK, Krämer OH, Knösel T, Engels K, Rödel F, Kovács AF, Dietmaier W, Klein-Hitpass L, Habtemichael N, Schweitzer A, Brieger J, Rödel C, Mann W, Petersen I, Heinzel T, Stauber RH. Knauer SK, et al. Among authors: kramer oh. FASEB J. 2007 Jan;21(1):207-16. doi: 10.1096/fj.06-5741com. Epub 2006 Nov 10. FASEB J. 2007. PMID: 17099069
A phosphorylation-acetylation switch regulates STAT1 signaling.
Krämer OH, Knauer SK, Greiner G, Jandt E, Reichardt S, Gührs KH, Stauber RH, Böhmer FD, Heinzel T. Krämer OH, et al. Genes Dev. 2009 Jan 15;23(2):223-35. doi: 10.1101/gad.479209. Genes Dev. 2009. PMID: 19171783 Free PMC article.
151 results