van Weeren L - Search Results

1

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

Goedhart J, von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, van Weeren L, Gadella TW Jr, Royant A. Goedhart J, et al. Among authors: van weeren l. Nat Commun. 2012 Mar 20;3:751. doi: 10.1038/ncomms1738. Nat Commun. 2012. PMID: 22434194 Free PMC article.

2

Sensitive detection of p65 homodimers using red-shifted and fluorescent protein-based FRET couples.

Goedhart J, Vermeer JE, Adjobo-Hermans MJ, van Weeren L, Gadella TW Jr. Goedhart J, et al. Among authors: van weeren l. PLoS One. 2007 Oct 10;2(10):e1011. doi: 10.1371/journal.pone.0001011. PLoS One. 2007. PMID: 17925859 Free PMC article.

3

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening.

Goedhart J, van Weeren L, Hink MA, Vischer NO, Jalink K, Gadella TW Jr. Goedhart J, et al. Among authors: van weeren l. Nat Methods. 2010 Feb;7(2):137-9. doi: 10.1038/nmeth.1415. Epub 2010 Jan 17. Nat Methods. 2010. PMID: 20081836

4

Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr. Adjobo-Hermans MJ, et al. Among authors: van weeren l. BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32. BMC Biol. 2011. PMID: 21619590 Free PMC article.

5

Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr. Goedhart J, et al. Among authors: van weeren l. PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17. PLoS One. 2011. PMID: 22114669 Free PMC article.

6

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr. Adjobo-Hermans MJ, et al. Among authors: van weeren l. Cell Signal. 2013 Jan;25(1):255-63. doi: 10.1016/j.cellsig.2012.09.022. Epub 2012 Sep 21. Cell Signal. 2013. PMID: 23006664

7

Optimization of fluorescent proteins.

Bindels DS, Goedhart J, Hink MA, van Weeren L, Joosen L, Gadella TW Jr. Bindels DS, et al. Among authors: van weeren l. Methods Mol Biol. 2014;1076:371-417. doi: 10.1007/978-1-62703-649-8_16. Methods Mol Biol. 2014. PMID: 24108635

8

mScarlet: a bright monomeric red fluorescent protein for cellular imaging.

Bindels DS, Haarbosch L, van Weeren L, Postma M, Wiese KE, Mastop M, Aumonier S, Gotthard G, Royant A, Hink MA, Gadella TW Jr. Bindels DS, et al. Among authors: van weeren l. Nat Methods. 2017 Jan;14(1):53-56. doi: 10.1038/nmeth.4074. Epub 2016 Nov 21. Nat Methods. 2017. PMID: 27869816

9

Multiparameter screening method for developing optimized red-fluorescent proteins.

Bindels DS, Postma M, Haarbosch L, van Weeren L, Gadella TWJ Jr. Bindels DS, et al. Among authors: van weeren l. Nat Protoc. 2020 Feb;15(2):450-478. doi: 10.1038/s41596-019-0250-7. Epub 2020 Jan 15. Nat Protoc. 2020. PMID: 31942080

10

Quantitative Determination of Dark Chromophore Population Explains the Apparent Low Quantum Yield of Red Fluorescent Proteins.

Prangsma JC, Molenaar R, van Weeren L, Bindels DS, Haarbosch L, Stouthamer J, Gadella TWJ Jr, Subramaniam V, Vos WL, Blum C. Prangsma JC, et al. Among authors: van weeren l. J Phys Chem B. 2020 Feb 27;124(8):1383-1391. doi: 10.1021/acs.jpcb.9b10396. Epub 2020 Feb 17. J Phys Chem B. 2020. PMID: 32011884 Free PMC article.

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