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Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q24.
Ishimaru S, Mimori K, Yamamoto K, Inoue H, Imoto S, Kawano S, Yamaguchi R, Sato T, Toh H, Iinuma H, Maeda T, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Sugihara K, Hase K, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Barnard GF, Miyano S, Mori M. Ishimaru S, et al. Among authors: iinuma h. Ann Surg Oncol. 2012 Sep;19(9):2853-8. doi: 10.1245/s10434-012-2278-6. Epub 2012 Mar 21. Ann Surg Oncol. 2012. PMID: 22434246
The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M. Takatsuno Y, et al. Among authors: iinuma h. Ann Surg Oncol. 2013 Apr;20(4):1395-402. doi: 10.1245/s10434-012-2657-z. Epub 2012 Sep 14. Ann Surg Oncol. 2013. PMID: 22976378
Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
Sugimachi K, Niida A, Yamamoto K, Shimamura T, Imoto S, Iinuma H, Shinden Y, Eguchi H, Sudo T, Watanabe M, Tanaka J, Kudo S, Hase K, Kusunoki M, Yamada K, Shimada Y, Sugihara K, Maehara Y, Miyano S, Mori M, Mimori K. Sugimachi K, et al. Among authors: iinuma h. Ann Surg Oncol. 2014 Dec;21 Suppl 4:S515-21. doi: 10.1245/s10434-013-3468-6. Epub 2014 Jan 6. Ann Surg Oncol. 2014. PMID: 24390711
Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis.
Yokobori T, Iinuma H, Shimamura T, Imoto S, Sugimachi K, Ishii H, Iwatsuki M, Ota D, Ohkuma M, Iwaya T, Nishida N, Kogo R, Sudo T, Tanaka F, Shibata K, Toh H, Sato T, Barnard GF, Fukagawa T, Yamamoto S, Nakanishi H, Sasaki S, Miyano S, Watanabe T, Kuwano H, Mimori K, Pantel K, Mori M. Yokobori T, et al. Among authors: iinuma h. Cancer Res. 2013 Apr 1;73(7):2059-69. doi: 10.1158/0008-5472.CAN-12-0326. Epub 2013 Feb 1. Cancer Res. 2013. PMID: 23378342
Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.
Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K. Uchi R, et al. Among authors: iinuma h. PLoS Genet. 2016 Feb 18;12(2):e1005778. doi: 10.1371/journal.pgen.1005778. eCollection 2016 Feb. PLoS Genet. 2016. PMID: 26890883 Free PMC article.
Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer.
Takano Y, Masuda T, Iinuma H, Yamaguchi R, Sato K, Tobo T, Hirata H, Kuroda Y, Nambara S, Hayashi N, Iguchi T, Ito S, Eguchi H, Ochiya T, Yanaga K, Miyano S, Mimori K. Takano Y, et al. Among authors: iinuma h. Oncotarget. 2017 Aug 7;8(45):78598-78613. doi: 10.18632/oncotarget.20009. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108252 Free PMC article.
272 results