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Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q24.
Ishimaru S, Mimori K, Yamamoto K, Inoue H, Imoto S, Kawano S, Yamaguchi R, Sato T, Toh H, Iinuma H, Maeda T, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Sugihara K, Hase K, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Barnard GF, Miyano S, Mori M. Ishimaru S, et al. Among authors: yamamoto k. Ann Surg Oncol. 2012 Sep;19(9):2853-8. doi: 10.1245/s10434-012-2278-6. Epub 2012 Mar 21. Ann Surg Oncol. 2012. PMID: 22434246
Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14.
Takahashi Y, Sugimachi K, Yamamoto K, Niida A, Shimamura T, Sato T, Watanabe M, Tanaka J, Kudo S, Sugihara K, Hase K, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Suzuki Y, Miyano S, Mori M, Mimori K. Takahashi Y, et al. Among authors: yamamoto k. Cancer Sci. 2017 Nov;108(11):2239-2247. doi: 10.1111/cas.13391. Epub 2017 Sep 26. Cancer Sci. 2017. PMID: 28869801 Free PMC article.
Genomic copy number of a carcinogenic single nucleotide polymorphism at 8q24 in non-risk allele colorectal cancer associated with insulin growth factor 2 receptor expression.
Takahashi Y, Mimori K, Yamamoto K, Watanabe M, Tanaka J, Kudo SE, Sugihara K, Hase K, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Mori M. Takahashi Y, et al. Among authors: yamamoto k. J Gastroenterol Hepatol. 2012 Apr;27 Suppl 3:95-9. doi: 10.1111/j.1440-1746.2012.07081.x. J Gastroenterol Hepatol. 2012. PMID: 22486879
The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M. Takatsuno Y, et al. Among authors: yamamoto k. Ann Surg Oncol. 2013 Apr;20(4):1395-402. doi: 10.1245/s10434-012-2657-z. Epub 2012 Sep 14. Ann Surg Oncol. 2013. PMID: 22976378
Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
Sugimachi K, Niida A, Yamamoto K, Shimamura T, Imoto S, Iinuma H, Shinden Y, Eguchi H, Sudo T, Watanabe M, Tanaka J, Kudo S, Hase K, Kusunoki M, Yamada K, Shimada Y, Sugihara K, Maehara Y, Miyano S, Mori M, Mimori K. Sugimachi K, et al. Among authors: yamamoto k. Ann Surg Oncol. 2014 Dec;21 Suppl 4:S515-21. doi: 10.1245/s10434-013-3468-6. Epub 2014 Jan 6. Ann Surg Oncol. 2014. PMID: 24390711
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
Tanaka F, Yamamoto K, Suzuki S, Inoue H, Tsurumaru M, Kajiyama Y, Kato H, Igaki H, Furuta K, Fujita H, Tanaka T, Tanaka Y, Kawashima Y, Natsugoe S, Setoyama T, Tokudome S, Mimori K, Haraguchi N, Ishii H, Mori M. Tanaka F, et al. Among authors: yamamoto k. Gut. 2010 Nov;59(11):1457-64. doi: 10.1136/gut.2009.205724. Epub 2010 Sep 9. Gut. 2010. PMID: 20833657
Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.
Sawada G, Niida A, Uchi R, Hirata H, Shimamura T, Suzuki Y, Shiraishi Y, Chiba K, Imoto S, Takahashi Y, Iwaya T, Sudo T, Hayashi T, Takai H, Kawasaki Y, Matsukawa T, Eguchi H, Sugimachi K, Tanaka F, Suzuki H, Yamamoto K, Ishii H, Shimizu M, Yamazaki H, Yamazaki M, Tachimori Y, Kajiyama Y, Natsugoe S, Fujita H, Mafune K, Tanaka Y, Kelsell DP, Scott CA, Tsuji S, Yachida S, Shibata T, Sugano S, Doki Y, Akiyama T, Aburatani H, Ogawa S, Miyano S, Mori M, Mimori K. Sawada G, et al. Among authors: yamamoto k. Gastroenterology. 2016 May;150(5):1171-1182. doi: 10.1053/j.gastro.2016.01.035. Epub 2016 Feb 10. Gastroenterology. 2016. PMID: 26873401 Free article.
Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.
Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K. Uchi R, et al. Among authors: yamamoto h, yamamoto k. PLoS Genet. 2016 Feb 18;12(2):e1005778. doi: 10.1371/journal.pgen.1005778. eCollection 2016 Feb. PLoS Genet. 2016. PMID: 26890883 Free PMC article.
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