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Deep annotation of mouse iso-miR and iso-moR variation.
Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS. Zhou H, et al. Among authors: henzler c. Nucleic Acids Res. 2012 Jul;40(13):5864-75. doi: 10.1093/nar/gks247. Epub 2012 Mar 19. Nucleic Acids Res. 2012. PMID: 22434881 Free PMC article.
Staged miRNA re-regulation patterns during reprogramming.
Henzler CM, Li Z, Dang J, Arcila ML, Zhou H, Liu J, Chang KY, Bassett DS, Rana TM, Kosik KS. Henzler CM, et al. Genome Biol. 2013 Dec 31;14(12):R149. doi: 10.1186/gb-2013-14-12-r149. Genome Biol. 2013. PMID: 24380417 Free PMC article.
Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment.
O'Callaghan B, Hofstra B, Handler HP, Kordasiewicz HB, Cole T, Duvick L, Friedrich J, Rainwater O, Yang P, Benneyworth M, Nichols-Meade T, Heal W, Ter Haar R, Henzler C, Orr HT. O'Callaghan B, et al. Among authors: henzler c. Mol Ther Nucleic Acids. 2020 Sep 4;21:1006-1016. doi: 10.1016/j.omtn.2020.07.030. Epub 2020 Jul 25. Mol Ther Nucleic Acids. 2020. PMID: 32818920 Free PMC article.
Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles.
Friedrich J, Kordasiewicz HB, O'Callaghan B, Handler HP, Wagener C, Duvick L, Swayze EE, Rainwater O, Hofstra B, Benneyworth M, Nichols-Meade T, Yang P, Chen Z, Ortiz JP, Clark HB, Öz G, Larson S, Zoghbi HY, Henzler C, Orr HT. Friedrich J, et al. Among authors: henzler c. JCI Insight. 2018 Nov 2;3(21):e123193. doi: 10.1172/jci.insight.123193. JCI Insight. 2018. PMID: 30385727 Free PMC article.
ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. Rousseaux MWC, et al. Among authors: henzler c. Neuron. 2018 Mar 21;97(6):1235-1243.e5. doi: 10.1016/j.neuron.2018.02.013. Epub 2018 Mar 8. Neuron. 2018. PMID: 29526553 Free PMC article.
Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
Pérez Ortiz JM, Mollema N, Toker N, Adamski CJ, O'Callaghan B, Duvick L, Friedrich J, Walters MA, Strasser J, Hawkinson JE, Zoghbi HY, Henzler C, Orr HT, Lagalwar S. Pérez Ortiz JM, et al. Among authors: henzler c. Neurobiol Dis. 2018 Aug;116:93-105. doi: 10.1016/j.nbd.2018.05.002. Epub 2018 May 11. Neurobiol Dis. 2018. PMID: 29758256 Free PMC article.
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors.
Irey EA, Lassiter CM, Brady NJ, Chuntova P, Wang Y, Knutson TP, Henzler C, Chaffee TS, Vogel RI, Nelson AC, Farrar MA, Schwertfeger KL. Irey EA, et al. Among authors: henzler c. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12442-12451. doi: 10.1073/pnas.1816410116. Epub 2019 May 30. Proc Natl Acad Sci U S A. 2019. PMID: 31147469 Free PMC article.
52 results