Jaeschke H - Search Results

1

Targeting autophagy for drug-induced hepatotoxicity.

Ni HM, Jaeschke H, Ding WX. Ni HM, et al. Among authors: jaeschke h. Autophagy. 2012 Apr;8(4):709-10. doi: 10.4161/auto.19659. Epub 2012 Apr 1. Autophagy. 2012. PMID: 22441014 Free PMC article.

2

Mechanisms of hepatotoxicity.

Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Jaeschke H, et al. Toxicol Sci. 2002 Feb;65(2):166-76. doi: 10.1093/toxsci/65.2.166. Toxicol Sci. 2002. PMID: 11812920 Review.

3

Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity.

Bajt ML, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: jaeschke h. J Pharmacol Exp Ther. 2008 Jan;324(1):8-14. doi: 10.1124/jpet.107.129445. Epub 2007 Sep 28. J Pharmacol Exp Ther. 2008. PMID: 17906064

4

Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine.

Saito C, Zwingmann C, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Hepatology. 2010 Jan;51(1):246-54. doi: 10.1002/hep.23267. Hepatology. 2010. PMID: 19821517 Free PMC article.

5

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

Saito C, Yan HM, Artigues A, Villar MT, Farhood A, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):182-90. doi: 10.1016/j.taap.2009.10.006. Epub 2009 Oct 14. Toxicol Appl Pharmacol. 2010. PMID: 19835899 Free PMC article.

6

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.

Saito C, Lemasters JJ, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Jul;246(1-2):8-17. doi: 10.1016/j.taap.2010.04.015. Epub 2010 Apr 25. Toxicol Appl Pharmacol. 2010. PMID: 20423716 Free PMC article.

7

Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice.

Williams CD, Bajt ML, Farhood A, Jaeschke H. Williams CD, et al. Among authors: jaeschke h. Liver Int. 2010 Oct;30(9):1280-92. doi: 10.1111/j.1478-3231.2010.02284.x. Liver Int. 2010. PMID: 20500806 Free PMC article.

8

Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury.

Williams CD, Farhood A, Jaeschke H. Williams CD, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Sep 15;247(3):169-78. doi: 10.1016/j.taap.2010.07.004. Epub 2010 Jul 15. Toxicol Appl Pharmacol. 2010. PMID: 20637792 Free PMC article.

9

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury.

Ramachandran A, Lebofsky M, Baines CP, Lemasters JJ, Jaeschke H. Ramachandran A, et al. Among authors: jaeschke h. Free Radic Res. 2011 Feb;45(2):156-64. doi: 10.3109/10715762.2010.520319. Epub 2010 Oct 13. Free Radic Res. 2011. PMID: 20942566 Free PMC article.

10

The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.

Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H. Ramachandran A, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2011 Mar 15;251(3):226-33. doi: 10.1016/j.taap.2011.01.004. Epub 2011 Jan 15. Toxicol Appl Pharmacol. 2011. PMID: 21241727 Free PMC article.

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