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Page 1
Linkage-disequilibrium-based binning affects the interpretation of GWASs.
Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S. Christoforou A, et al. Among authors: le hellard s. Am J Hum Genet. 2012 Apr 6;90(4):727-33. doi: 10.1016/j.ajhg.2012.02.025. Epub 2012 Mar 22. Am J Hum Genet. 2012. PMID: 22444669 Free PMC article.
Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
Le Hellard S, Lee AJ, Underwood S, Thomson PA, Morris SW, Torrance HS, Anderson SM, Adams RR, Navarro P, Christoforou A, Houlihan LM, Detera-Wadleigh S, Owen MJ, Asherson P, Muir WJ, Blackwood DH, Wray NR, Porteous DJ, Evans KL. Le Hellard S, et al. Biol Psychiatry. 2007 Mar 15;61(6):797-805. doi: 10.1016/j.biopsych.2006.06.029. Epub 2006 Sep 25. Biol Psychiatry. 2007. PMID: 16996484
Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
Le Hellard S, Theisen FM, Haberhausen M, Raeder MB, Fernø J, Gebhardt S, Hinney A, Remschmidt H, Krieg JC, Mehler-Wex C, Nöthen MM, Hebebrand J, Steen VM. Le Hellard S, et al. Mol Psychiatry. 2009 Mar;14(3):308-17. doi: 10.1038/sj.mp.4002133. Epub 2008 Jan 15. Mol Psychiatry. 2009. PMID: 18195716
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples.
Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM. Le Hellard S, et al. Mol Psychiatry. 2010 May;15(5):463-72. doi: 10.1038/mp.2008.110. Epub 2008 Oct 21. Mol Psychiatry. 2010. PMID: 18936756
Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.
Le Hellard S, Håvik B, Espeseth T, Breilid H, Løvlie R, Luciano M, Gow AJ, Harris SE, Starr JM, Wibrand K, Lundervold AJ, Porteous DJ, Bramham CR, Deary IJ, Reinvang I, Steen VM. Le Hellard S, et al. PLoS One. 2009 Oct 21;4(10):e7534. doi: 10.1371/journal.pone.0007534. PLoS One. 2009. PMID: 19844571 Free PMC article.
Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p.
Christoforou A, McGhee KA, Morris SW, Thomson PA, Anderson S, McLean A, Torrance HS, Le Hellard S, Pickard BS, StClair D, Muir WJ, Blackwood DH, Porteous DJ, Evans KL. Christoforou A, et al. Among authors: le hellard s. Mol Psychiatry. 2011 Mar;16(3):240-2. doi: 10.1038/mp.2010.25. Epub 2010 Mar 30. Mol Psychiatry. 2011. PMID: 20351716 No abstract available.
111 results