Zhang W - Search Results

1

QT effect of semagacestat at therapeutic and supratherapeutic doses.

Zhang W, Ayan-Oshodi M, Willis BA, Annes W, Hall SD, Chiesa J, Seger M. Zhang W, et al. Int J Clin Pharmacol Ther. 2012 Apr;50(4):290-9. doi: 10.5414/cp201672. Int J Clin Pharmacol Ther. 2012. PMID: 22456300 Clinical Trial.

2

Semagacestat pharmacokinetics are not significantly affected by formulation, food, or time of dosing in healthy participants.

Willis BA, Zhang W, Ayan-Oshodi M, Lowe SL, Annes WF, Sirois PJ, Friedrich S, de la Peña A. Willis BA, et al. Among authors: zhang w. J Clin Pharmacol. 2012 Jun;52(6):904-13. doi: 10.1177/0091270011407195. Epub 2011 Jul 1. J Clin Pharmacol. 2012. PMID: 21724950 Clinical Trial.

3

The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.

Ayan-Oshodi MA, Willis BA, Annes WF, Lowe SL, Friedrich S, de la Peña A, Zhang W, Brown T, Wise SD, Hall SD. Ayan-Oshodi MA, et al. Among authors: zhang w. Drug Metab Dispos. 2012 Oct;40(10):1945-52. doi: 10.1124/dmd.112.046060. Epub 2012 Jul 12. Drug Metab Dispos. 2012. PMID: 22789530 Clinical Trial.

4

Effect of pomaglumetad methionil on the QT interval in subjects with schizophrenia.

Zhang W, Mitchell MI, Knadler MP, Long A, Witcher J, Walling D, Annes W, Ayan-Oshodi M. Zhang W, et al. Int J Clin Pharmacol Ther. 2015 Jun;53(6):462-70. doi: 10.5414/CP202289. Int J Clin Pharmacol Ther. 2015. PMID: 25881753 Clinical Trial.

5

Relative contributions of presystemic and systemic peptidases to oral exposure of a novel metabotropic glutamate 2/3 receptor agonist (LY404039) after oral administration of prodrug pomaglumetad methionil (LY2140023).

Annes WF, Long A, Witcher JW, Ayan-Oshodi MA, Knadler MP, Zhang W, Mitchell MI, Cornelissen K, Hall SD. Annes WF, et al. Among authors: zhang w. J Pharm Sci. 2015 Jan;104(1):207-14. doi: 10.1002/jps.24226. Epub 2014 Nov 7. J Pharm Sci. 2015. PMID: 25382826 Clinical Trial.

6

Evacetrapib at a supratherapeutic steady state concentration does not prolong QT in a thorough QT/QTc study in healthy participants.

Suico JG, Friedrich S, Krueger KA, Zhang W. Suico JG, et al. Among authors: zhang w. J Cardiovasc Pharmacol Ther. 2014 May;19(3):283-9. doi: 10.1177/1074248413510784. Epub 2013 Nov 22. J Cardiovasc Pharmacol Ther. 2014. PMID: 24271137 Clinical Trial.

7

A Multidose Study to Examine the Effect of Food on Evacetrapib Exposure at Steady State.

Small DS, Zhang W, Royalty J, Cannady EA, Downs D, Friedrich S, Suico JG. Small DS, et al. Among authors: zhang w. J Cardiovasc Pharmacol Ther. 2015 Sep;20(5):483-9. doi: 10.1177/1074248415575153. Epub 2015 Mar 3. J Cardiovasc Pharmacol Ther. 2015. PMID: 25736283 Free PMC article. Clinical Trial.

8

Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib.

Small DS, Zhang W, Royalty J, Cannady EA, Downs D, Ortega D, Suico JG. Small DS, et al. Among authors: zhang w. Eur J Clin Pharmacol. 2016 May;72(5):563-72. doi: 10.1007/s00228-016-2017-1. Epub 2016 Feb 9. Eur J Clin Pharmacol. 2016. PMID: 26857125 Free PMC article. Clinical Trial.

9

Evaluation of the likelihood of a selective CHK1 inhibitor (LY2603618) to inhibit CYP2D6 with desipramine as a probe substrate in cancer patients.

Hynes SM, Wickremsinhe E, Zhang W, Decker R, Ott J, Chandler J, Mitchell M. Hynes SM, et al. Among authors: zhang w. Biopharm Drug Dispos. 2015 Jan;36(1):49-63. doi: 10.1002/bdd.1922. Epub 2014 Nov 14. Biopharm Drug Dispos. 2015. PMID: 25296725 Clinical Trial.

10

A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer.

Sullivan RJ, Hollebecque A, Flaherty KT, Shapiro GI, Rodon Ahnert J, Millward MJ, Zhang W, Gao L, Sykes A, Willard MD, Yu D, Schade AE, Crowe K, Flynn DL, Kaufman MD, Henry JR, Peng SB, Benhadji KA, Conti I, Gordon MS, Tiu RV, Hong DS. Sullivan RJ, et al. Among authors: zhang w. Mol Cancer Ther. 2020 Feb;19(2):460-467. doi: 10.1158/1535-7163.MCT-19-0681. Epub 2019 Oct 23. Mol Cancer Ther. 2020. PMID: 31645440 Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

87,352 results

Search Page

Filters