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The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691).
Fidock MD, Souberbielle BE, Laxton C, Rawal J, Delpuech-Adams O, Corey TP, Colman P, Kumar V, Cheng JB, Wright K, Srinivasan S, Rana K, Craig C, Horscroft N, Perros M, Westby M, Webster R, van der Ryst E. Fidock MD, et al. Among authors: rawal j. Clin Pharmacol Ther. 2011 Jun;89(6):821-9. doi: 10.1038/clpt.2011.60. Epub 2011 Mar 30. Clin Pharmacol Ther. 2011. PMID: 21451504 Clinical Trial.
Preclinical studies of PF-04849285, an interferon-α8 fusion protein for the treatment of HCV.
Flores MV, Hickling TP, Sreckovic S, Fidock MD, Horscroft N, Katragadda M, Savic B, Rawal J, Delpuech-Adams OE, Robas N, Corey T, Nelms L, Lawton M, Marcek J, Stubbs M, Westby M, Ciaramella G. Flores MV, et al. Among authors: rawal j. Antivir Ther. 2012;17(5):869-81. doi: 10.3851/IMP2099. Epub 2012 Apr 13. Antivir Ther. 2012. PMID: 22505586
Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome entry site.
Laxton C, Brady K, Moschos S, Turnpenny P, Rawal J, Pryde DC, Sidders B, Corbau R, Pickford C, Murray EJ. Laxton C, et al. Among authors: rawal j. Antimicrob Agents Chemother. 2011 Jul;55(7):3105-14. doi: 10.1128/AAC.00222-11. Epub 2011 Apr 18. Antimicrob Agents Chemother. 2011. PMID: 21502629 Free PMC article.
Design and optimisation of potent gp120-CD4 inhibitors.
Tran TD, Adam FM, Calo F, Fenwick DR, Fok-Seang J, Gardner I, Hay DA, Perros M, Rawal J, Middleton DS, Parkinson T, Pickford C, Platts M, Randall A, Stephenson PT, Vuong H, Williams DH. Tran TD, et al. Among authors: rawal j. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5250-5. doi: 10.1016/j.bmcl.2009.06.102. Epub 2009 Jul 4. Bioorg Med Chem Lett. 2009. PMID: 19632839
68 results