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Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs.
Yoshihara H, Fukushima T, Hakuno F, Saeki Y, Tanaka K, Ito A, Yoshida M, Iemura S, Natsume T, Asano T, Chida K, Girnita L, Takahashi S. Yoshihara H, et al. Biochem Biophys Res Commun. 2012 Jun 22;423(1):122-7. doi: 10.1016/j.bbrc.2012.05.093. Epub 2012 May 23. Biochem Biophys Res Commun. 2012. PMID: 22634009
Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.
Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K. Kiefer H, et al. J Biol Chem. 2009 Apr 17;284(16):10694-705. doi: 10.1074/jbc.M807136200. Epub 2009 Feb 18. J Biol Chem. 2009. PMID: 19224921 Free PMC article.
109 results