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Regulation of bile acid synthesis by fat-soluble vitamins A and D.
Schmidt DR, Holmstrom SR, Fon Tacer K, Bookout AL, Kliewer SA, Mangelsdorf DJ. Schmidt DR, et al. J Biol Chem. 2010 May 7;285(19):14486-94. doi: 10.1074/jbc.M110.116004. Epub 2010 Mar 16. J Biol Chem. 2010. PMID: 20233723 Free PMC article.
AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.
Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. Schmidt DR, et al. Among authors: schmidt s. J Biol Chem. 2011 Jan 28;286(4):2425-32. doi: 10.1074/jbc.M110.181230. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081494 Free PMC article.
International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.
Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA. Moore DD, et al. Among authors: schmidt dr. Pharmacol Rev. 2006 Dec;58(4):742-59. doi: 10.1124/pr.58.4.6. Pharmacol Rev. 2006. PMID: 17132852 Review.
101 results