Giese A - Search Results

1

Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state.

Högen T, Levin J, Schmidt F, Caruana M, Vassallo N, Kretzschmar H, Bötzel K, Kamp F, Giese A. Högen T, et al. Among authors: giese a. Biophys J. 2012 Apr 4;102(7):1646-55. doi: 10.1016/j.bpj.2012.01.059. Epub 2012 Apr 3. Biophys J. 2012. PMID: 22500765 Free PMC article.

2

Converse modulation of toxic alpha-synuclein oligomers in living cells by N'-benzylidene-benzohydrazide derivates and ferric iron.

Hillmer AS, Putcha P, Levin J, Högen T, Hyman BT, Kretzschmar H, McLean PJ, Giese A. Hillmer AS, et al. Among authors: giese a. Biochem Biophys Res Commun. 2010 Jan 1;391(1):461-6. doi: 10.1016/j.bbrc.2009.11.080. Epub 2009 Nov 13. Biochem Biophys Res Commun. 2010. PMID: 19914207 Free PMC article.

3

Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes.

Schmidt F, Levin J, Kamp F, Kretzschmar H, Giese A, Bötzel K. Schmidt F, et al. Among authors: giese a. PLoS One. 2012;7(8):e42545. doi: 10.1371/journal.pone.0042545. Epub 2012 Aug 3. PLoS One. 2012. PMID: 22880029 Free PMC article.

4

Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers.

Nübling GS, Levin J, Bader B, Lorenzl S, Hillmer A, Högen T, Kamp F, Giese A. Nübling GS, et al. Among authors: giese a. PLoS One. 2014 Jun 9;9(6):e98906. doi: 10.1371/journal.pone.0098906. eCollection 2014. PLoS One. 2014. PMID: 24911099 Free PMC article.

5

Intracellular formation of α-synuclein oligomers and the effect of heat shock protein 70 characterized by confocal single particle spectroscopy.

Levin J, Hillmer AS, Högen T, McLean PJ, Giese A. Levin J, et al. Among authors: giese a. Biochem Biophys Res Commun. 2016 Aug 12;477(1):76-82. doi: 10.1016/j.bbrc.2016.06.023. Epub 2016 Jun 7. Biochem Biophys Res Commun. 2016. PMID: 27286709

6

Different Effects of α-Synuclein Mutants on Lipid Binding and Aggregation Detected by Single Molecule Fluorescence Spectroscopy and ThT Fluorescence-Based Measurements.

Ruf VC, Nübling GS, Willikens S, Shi S, Schmidt F, Levin J, Bötzel K, Kamp F, Giese A. Ruf VC, et al. Among authors: giese a. ACS Chem Neurosci. 2019 Mar 20;10(3):1649-1659. doi: 10.1021/acschemneuro.8b00579. Epub 2019 Jan 16. ACS Chem Neurosci. 2019. PMID: 30605594

7

Effect of metal ions on de novo aggregation of full-length prion protein.

Giese A, Levin J, Bertsch U, Kretzschmar H. Giese A, et al. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1240-6. doi: 10.1016/j.bbrc.2004.06.075. Biochem Biophys Res Commun. 2004. PMID: 15249223

8

Breakage of PrP aggregates is essential for efficient autocatalytic propagation of misfolded prion protein.

Piening N, Weber P, Giese A, Kretzschmar H. Piening N, et al. Among authors: giese a. Biochem Biophys Res Commun. 2005 Jan 14;326(2):339-43. doi: 10.1016/j.bbrc.2004.11.039. Biochem Biophys Res Commun. 2005. PMID: 15582583

9

Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln.

Stork M, Giese A, Kretzschmar HA, Tavan P. Stork M, et al. Among authors: giese a. Biophys J. 2005 Apr;88(4):2442-51. doi: 10.1529/biophysj.104.052415. Epub 2005 Jan 21. Biophys J. 2005. PMID: 15665127 Free PMC article.

10

Single particle analysis of manganese-induced prion protein aggregates.

Levin J, Bertsch U, Kretzschmar H, Giese A. Levin J, et al. Among authors: giese a. Biochem Biophys Res Commun. 2005 Apr 22;329(4):1200-7. doi: 10.1016/j.bbrc.2005.02.094. Biochem Biophys Res Commun. 2005. PMID: 15766554

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