Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

10 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM. Skidmore J, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2012 May 15;22(10):3531-4. doi: 10.1016/j.bmcl.2012.03.062. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22503453
Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM. Skidmore J, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2012 May 15;22(10):3560-3. doi: 10.1016/j.bmcl.2012.03.040. Epub 2012 Mar 16. Bioorg Med Chem Lett. 2012. PMID: 22503248
The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.
Giblin GM, Bit RA, Brown SH, Chaignot HM, Chowdhury A, Chessell IP, Clayton NM, Coleman T, Hall A, Hammond B, Hurst DN, Michel AD, Naylor A, Novelli R, Scoccitti T, Spalding D, Tang SP, Wilson AW, Wilson R. Giblin GM, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2007 Jan 15;17(2):385-9. doi: 10.1016/j.bmcl.2006.10.041. Epub 2006 Oct 20. Bioorg Med Chem Lett. 2007. PMID: 17084082
Novel methylene-linked heterocyclic EP1 receptor antagonists.
Hall A, Bit RA, Brown SH, Chowdhury A, Giblin GM, Hurst DN, Kilford IR, Lewell X, Naylor A, Scoccitti T. Hall A, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1592-7. doi: 10.1016/j.bmcl.2008.01.071. Epub 2008 Jan 19. Bioorg Med Chem Lett. 2008. PMID: 18262416
Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping.
Hall A, Billinton A, Brown SH, Chowdhury A, Giblin GM, Goldsmith P, Hurst DN, Naylor A, Patel S, Scoccitti T, Theobald PJ. Hall A, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2684-90. doi: 10.1016/j.bmcl.2008.03.018. Epub 2008 Mar 10. Bioorg Med Chem Lett. 2008. PMID: 18378447
Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.
Hall A, Billinton A, Brown SH, Chowdhury A, Clayton NM, Giblin GM, Gibson M, Goldsmith PA, Hurst DN, Naylor A, Peet CF, Scoccitti T, Wilson AW, Winchester W. Hall A, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2009 May 1;19(9):2599-603. doi: 10.1016/j.bmcl.2009.02.112. Epub 2009 Mar 3. Bioorg Med Chem Lett. 2009. PMID: 19332369
Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists.
Allan AC, Billinton A, Brown SH, Chowdhury A, Eatherton AJ, Fieldhouse C, Giblin GM, Goldsmith P, Hall A, Hurst DN, Naylor A, Rawlings DA, Sime M, Scoccitti T, Theobald PJ. Allan AC, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4343-8. doi: 10.1016/j.bmcl.2011.05.047. Epub 2011 May 23. Bioorg Med Chem Lett. 2011. PMID: 21676612
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor.
Abberley L, Bebius A, Beswick PJ, Billinton A, Collis KL, Dean DK, Fonfria E, Gleave RJ, Medhurst SJ, Michel AD, Moses AP, Patel S, Roman SA, Scoccitti T, Smith B, Steadman JG, Walter DS. Abberley L, et al. Among authors: scoccitti t. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6370-4. doi: 10.1016/j.bmcl.2010.09.101. Epub 2010 Sep 22. Bioorg Med Chem Lett. 2010. PMID: 20934331